Generic Name : Edrophonium Injection Pronunciation : ED roe FOE nee um Therapeutic Classification : Diagnostic Agents ICD Code : Y57.6
International- Enlon, Tensilon, Reversol. Why it is prescribed (Indications) :
This medication is an acetylcholinesterase inhibitor, prescribed for diagnosis of myasthenia gravis. It prevents the breakdown of the neurotransmitter acetylcholine. When it is not to be taken (Contraindications):
Contraindicated in patients with intestinal, urinary obstruction; and hypersensitivity.
Dosage & When it is to be taken :
Adults- IV- The recommended dose is 1 mL (10 mg) and prepared with an intravenous needle, and 0.2 mL (2 mg) is injected intravenously within 15 to 30 seconds. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of asthma, heart rhythm disorder, any allergy, and during pregnancy and breastfeeding. Side Effects :
Eye - Increased tears, pupillary constriction, spasm of accommodation, double visionand conjunctival hyperemia.
Central Nervous System - Convulsions, speech disorder, voice disorder and difficulty in understanding.
Respiratory - Asthma, airway obstruction and central respiratory paralysis.
Heart - Abnormal heart rhythm, low blood pressure and increased salivation.
Gastrointestinal - Gastric and intestinal secretion, nausea, vomiting, increased peristalsis, diarrhea and abdominal cramps.
Musculoskeletal - Weakness and muscle twitch.
Miscellaneous - Increased urinary frequency and incontinence, increased sweating.
* Avoid excess dosage. Storage Conditions :
Store it at controlled room temperature (15°-30°C).
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