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Edetate

Latest prescription information about Edetate. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Edetate
Pronunciation : E de tate dye SOE dee um
Therapeutic Classification : Chelating Agents
ICD Code : Y57.2
Trade Name(s): 
International- Endrate.
Why it is prescribed (Indications) : 
This medication is a chelating agent, prescribed for hypercalcemia and for the control of ventricular arrhythmias associated with digitalis toxicity in emergency. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with anuria, and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
For Adults: The recommended daily dosage is 50 mg/kg of body weight to a maximum dose of 3 g in 24 hours.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart disease, congestive heart failure, abnormal heart rhythm, diabetes, low potassium levels, seizures, brain tumor, recent head injury, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Side Effects : 
Gastrointestinal - Nausea, vomiting and diarrhea.
Miscellaneous - Tingling, numbness and headache.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C).


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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