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Ecallantide

Latest prescription information about Ecallantide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Ecallantide
Pronunciation : e-KAL-lan-tide
Therapeutic Classification : Kallikrein Inhibitor
Trade Name(s): 
International- Kalbitor.
Why it is prescribed (Indications) : 
This medication is a human plasma kallikrein inhibitor, prescribed for sudden attacks of hereditary angioedema (HAE).  It blocks the substances that cause swelling, inflammation, and pain.
When it is not to be taken (Contraindications): 
Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
SC- The recommended dose is 30 mg (3 mL), 3 times per day.
How it should be taken : 
It comes as a solution for injection, to be administered by a healthcare provider under the skin.
Warnings and Precautions : 
* Caution should be exercised in patients with any allergy, during pregnancy and breastfeeding.
Side Effects : 
Headache, nausea, fatigue, diarrhea, upper respiratory tract infection, injection site reactions, vomiting, itching, abdominal pain and fever.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2°C to 8°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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