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Duloxetine

Latest prescription information about Duloxetine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Duloxetine
Pronunciation : doo lox' e teen
Trade Name(s): 
India- 2-Dep Tab, C-Pact Cap, Delok Cap, Dlx Tab, Dulane Cap, Dulex Cap, Dulife Cap, Dulocin Tab, Dulojoy Tab, Dulot Cap, Dumore Cap, Duotop Cap, Dupact Cap, Dureep Cap, Dutin Cap, Duvanta Tab, Duxet Cap, Duzac Cap, Duzela Cap, Mydula Tab, Nudep-20 Hg-Cap, Nudep-30 Hg-Cap, Nudep-40 Cap, Swenta Tab, Sylonex Enteric-Coated Tab, Symbal Tab, Symbal-M Tab, Sympta Tab, Verlox Enteric-Coated Tab.
International-Cymbalta, Ariclaim, Xeristar, Yentreve, Duzela.
Why it is prescribed (Indications) : 
This medication is a serotonin-norepinephrine reuptake inhibitor, prescribed for depression, anxiety disorder, and also used for managing pain caused by fibromyalgia and diabetic peripheral neuropathy (DPNP). It maintains the mental balance and stops the movement of pain signals in the brain.

When it is not to be taken (Contraindications): 


Contraindicated during pregnancy and breastfeeding, patients may experience side effects like increased intraocular tension, liver damage, and kidney failure.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
PO- The recommended dose is 40 to 60mg/day, twice daily orally.
How it should be taken : 
It comes capsule to take by mouth. It is usually taken once or twice a day with or without food. (Swallow whole, do not chew/crush).
Special Instruction : 
*Avoid alcohol because alcohol can increase the risk of serious side effects from this medication.
*It may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position. Get up slowly from bed.
*May make you drowsy, dizzy, or may affect your judgment, thinking or coordination. Do not drive a car or operate machinery while taking this medication.
*Contact the doctor right away if any signs of suicidal thoughts or actions occur.
*Check blood sugar levels closely
Side Effects : 
Heart- Hot flush, palpitations, heart attack, hypertensive crisis, abnormal heart rhythm.
Central Nervous System- Drowsiness, headache, dizziness, sleeplessness, fatigue, decreased appetite, lack of energy, agitation, tremor, decreased sexual activities, tingling, abnormal dreams, anxiety, migraine, elevated body temperature, sleep disorder, yawning, partial loss of sensitivity, lethargy, vertigo, aggression, anger, restless leg syndrome, seizures upon treatment discontinuation.
Skin- Abnormally increased perspiration, rash, itching, redness of the skin.
Eye and ENT- Nasopharynx inflammation, pharynx and larynx pain, blurred vision, sudden eye pressure, perception of sound within the human ear in the absence of corresponding external sound
Gastrointestinal- Nausea, dry mouth, constipation, diarrhea, vomiting, upset stomach, abdominal pain, loose stools, stomach flu, flatulence.
Genitourinary- Impotence, frequent daytime urination, ejaculation disorder, abnormal orgasm, delayed ejaculation, urinary tract infection, penis disorder, sexual dysfunction, abnormal uterine bleeding.
Hypersensitivity- Anaphylactic reaction, rapid swelling (edema) of the dermis, hypersensitivity.
Metabolic- Loss of appetite, decreased weight, increased weight, increased sugar level in blood.
Musculoskeletal- Muscle cramps, musculoskeletal pain, muscle spasm, muscle pain.
Respiratory- Upper respiratory tract infection, cough.
Miscellaneous- Fever, seasonal allergy, influenza, chill/rigors.
Other Precautions : 
*Consult your doctor for dosage changes.
Storage Conditions : 
Store at 25°C. Store it in air tight container and keep away from children.

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