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Doxorubicin

Updated on : September - 2012
Latest prescription information about Doxorubicin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Doxorubicin
Pronunciation : dox oh roo' bi sin
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Adriamycin Vial, Adrim Inj, Adrosal Vial, Cadria Vial, Caelyx Vial, Cardia Vial, Dobicin Vial, Dobixin Inj, Doxilyd Inj, Doxobin Vial, Doxolem Vial, Doxomed Vial, Doxorex Vial, Doxorubicin Vial, Doxorubicin-Inj Vial, Doxorubin Vial, Doxulip Vial, Doxutec Vial, Duxocin Inj, Lyphidox Vial, Naprodox Vial, Oncodox Inj, Oncodria Vial, Rubinat Vial, Tevadox Inj, Tumodox Inj, Zodox Vial.
International- Adriamycin PFS, Adriamycin RDF, Adriamycin, Doxil, Rubex.
Why it is prescribed (Indications) : 
This medication is a cytotoxic anthracycline antibiotic, prescribed for treating various types of cancer. It works by killing cancer cells.
When it is not to be taken (Contraindications): 
Contraindicated in patients with heart problem, who have previously received treatment with other anticancer medicines, decreased blood counts, bone marrow depression and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult- IV- The recommended dose is 60-75 mg once in 21 days or 30 mg daily for 3 days every four weeks.
How it should be taken : 
It comes as solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart or blood vessel disease or liver problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
* It may reduce platelet counts which leads to severe bleeding; avoid bruising and bleeding.
* Avoid vaccination while taking this medication.
Side Effects : 
Severe Effects - Heart failure and gastrointestinal bleeding.
Gastrointestinal - Loss of appetite, abdominal pain, dehydration, diarrhea, nausea and vomiting.
Skin - Pigmentation, rash, itching and light sensitivity.
Other Precautions : 
* Avoid contact with persons with known infections.
* Do not drink alcoholic beverages or take drugs containing aspirin because these can cause gastric bleeding.
Storage Conditions : 
Store powder at room temperature.

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Member Comments ( 1 )
this is the best information on doxorubicin ever i met
(Posted by peters, India Date : 3/25/2011 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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