Trade Names/Brand Names :
Adriamycin PFS, Adriamycin RDF, Adriamycin, Doxil, Rubex
Why it is prescribed :
This medication is a cytotoxic anthracycline antibiotic, prescribed for treating various types of cancer. It works by killing cancer cells.
When it is not to be taken (Contraindications):
Contraindicated in patients with heart problem, who have previously received treatment with other anticancer medicines, decreased blood counts, bone marrow depression and hypersensitivity.
Category D :
There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.
Dosage & When it is to be taken (Indications):
Adult- IV- The recommended dose is 60-75 mg once in 21 days or 30 mg daily for 3 days every four weeks.
How it should be taken :
It comes as solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions :
• Caution should be exercised in patients with history of heart or blood vessel disease or liver problems, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
It may reduce platelet counts which leads to severe bleeding; avoid bruising and bleeding.
Avoid vaccination while taking this medication.
Side Effects :
• Severe Effects
Heart failure and gastrointestinal bleeding.
Loss of appetite, abdominal pain, dehydration, diarrhea, nausea and vomiting.
Pigmentation, rash, itching and light sensitivity.
Other Precautions :
Avoid contact with persons with known infections.
Do not drink alcoholic beverages or take drugs containing aspirin because these can cause gastric bleeding.
Storage Conditions :
Store powder at room temperature.
Schedule : G
Drugs that are to be used only under medical supervision.