Doxepin

Latest prescription information about Doxepin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Doxepin
Pronunciation : dox' e pin
Therapeutic Classification : psychotherapeutics
Trade Name(s): 
India- Doxedep Film-Coated Tab, Doxetar Cap, Doxetar F-Cap, Doxin Cap, Doxure Cream, Doxyril Tab, Noctaderm Cream, Spectra Cap.
International- Adapin, Silenor.
Why it is prescribed (Indications) : 
This medication is an antidepressant, prescribed for depression.

When it is not to be taken (Contraindications): 


Contraindicated in patients with increased eye pressure, urinary retention and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Adult: PO- Initial: 75 mg/day, up to 300 mg/day in severely depressed patients. Total daily dose is more than 100 mg should be given in divided doses.
How it should be taken : 
It comes as a capsule and syrup to take by mouth, with or without food.
Special Instruction : 
* Caution should be exercised in patients with history of enlarged prostate, diabetes, seizures, an overactive thyroid gland, liver, kidney or heart disease, any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.
* It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Anticholinergic Effects - Dry mouth, blurred vision, constipation and urinary retention.
Central Nervous System - Drowsiness, confusion, disorientation, hallucinations, numbness, tingling, incoordination, seizures, tardive dyskinesia and tremor.
Heart - Low/high blood pressure and fast heart rate.
Allergic - Skin rash, swelling in the face, lips, eyes, mouth, light sensitivity and itching.
Blood - Eosinophilia, bone marrow depression and bruising.
Gastrointestinal - Nausea, vomiting, indigestion, taste disturbances, diarrhea and loss of appetite.
Genitourinary - Raised or lowered sexual drive, testicular swelling, breast enlargement in males, spontaneous milk secretion in females and raising or lowering of blood sugar levels.
Miscellaneous - Dizziness, ringing in the ear, weight gain, increased sweating, chills, fatigue, weakness, flushing, jaundice, hair loss, headache and fever.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature, and in an airtight container.

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