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Doxazosin

Latest prescription information about Doxazosin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Doxazosin
Pronunciation : dox ay' zoe sin
Therapeutic Classification : BPH Agents
Trade Name(s): 
India- Alfazosin Tab, Doxacard Tab, Doxapress Tab, Duracard Tab, Duraten Tab.
International- Cardura.
Why it is prescribed (Indications) : 
This medication is an alpha blocker, prescribed for high blood pressure and benign prostatic hyperplasia (an enlarged prostate). It relaxes the muscles around the urethra and decreases chances of surgery. 
When it is not to be taken (Contraindications): 
Known hypersensitivity to quinazolines.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
HTN- Initial: 1 mg/day at bedtime. Maintenance: 4 mg once daily. Max: 16 mg/day.
Benign prostatic hyperplasia- Initial: 1 mg/day at bedtime. Maintenance: 2 to 4 mg/day. Max: 8 mg/day by oral.
How it should be taken : 
This medication available in the form of tablet to take by mouth, usually taken with or without food once a day in the morning or in the evening.
Warnings and Precautions : 
*Prostate cancer should be ruled out before starting therapy.
*Orthostatic hypotension may occur at the initiation of therapy or when there is dose increase.
*Avoid driving or performing hazardous tasks for 24 hour after starting therapy or dose changes.
*Consult with your doctor during Pregnancy and breastfeeding.
Side Effects : 
Heart- Irregular heart beat, chest pain.
Genitourinary- Decreased sexual ability, painful erection of the penis that lasts for hours.
Miscellaneous- Headache, tiredness, swelling of the mouth, shortness of breath, weight gain, joint pain, abnormal vision, runny nose, hives.
Other Precautions : 
*Monitor blood pressure and pulse regularly while taking this medication.
Storage Conditions : 
Store at 25°C. Store it in airtight container.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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