Dothiepin - Drug InformationGeneric Name : Dothiepin
International :Dopress, Dothep, Espin, Harmomed, Idom, Prothiaden, Protiaden, Sandoz Dothiepin HCl, Thaden
Other Name :Dosulepin
Why it is prescribed (Indications) :
This medication is an antidepressant, prescribed for depression.
When it is not to be taken (Contraindications):Contraindicated in patients with hypersensitivity, recent heart attack, neonates, heart block, abnormal heart rhythm, mania, alcohol, other CNS depressants, severe liver disease, prostate disease and in children.
Pregnancy Category :
Category C :Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Dosage & When it is to be taken :
Adult: PO- Initial: 25 mg 3 times/day, up to 225 mg/day may be used in severe depression.
How it should be taken :
It comes as a tablet to take by mouth, with food.
Warnings and Precautions :Caution should be exercised in patients with history of epilepsy, high blood pressure, increased eye pressure, urinary retention, gradual withdrawal, elderly, during pregnancy and breastfeeding.
Side Effects :
Most Common - Dizziness, blurred vision, fast heart rate, urinary retention, tremor, blood disorders, low blood pressure, sexual dysfunction and sweating.
Miscellaneous - Nausea, vomiting, loss of appetite, headache, giddiness, chills, sleeplessness and anxiety.