Generic Name : Donepezil Pronunciation : doe nep e zil Therapeutic Classification : Anti- Alzheimer's Agents ICD Code : Y51.8
India- Aricep, Depzil, Donasure, Donaz, Donecept, Donep, Donice, Dopezil, Dorent, Nozil-10.
International- Aricept, Aricept ODT. Why it is prescribed (Indications) :
This medication is a cholinesterase inhibitor, prescribed for dementia of Alzheimer's disease. It works by increasing the amount of acetylcholine in the brain, which helps in improving mental function. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
Adult: PO- Initial: 5 mg/day in the evening, up to 10 mg/day after 4-6 week. How it should be taken :
It comes as a tablet to take by mouth, with or without food. Warnings and Precautions :
* Caution should be exercised in patients with history of heart disease, stomach problems, liver or kidney disease, breathing problems, urinary obstruction, brain tumor, head injury, seizures, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause drowsiness, dizziness, or fainting, do not drive a car or operate machinery while taking this medication.
* It should not be used in children. Side Effects :
Most frequent - Nausea, diarrhea, vomiting, muscle cramps, fatigue and loss of appetite.
Body as a Whole - Headache, generalized pain and fatigue.
Heart - Fainting.
Blood - Bruising.
Metabolic - Decreased weight.
Musculoskeletal - Muscle cramps and joint inflammation.
Central Nervous System - Sleeplessness, dizziness, depression, abnormal dreams and drowsiness.
Genitourinary - Frequent urination.
* Avoid excess dosage. Storage Conditions :
Store it at controlled room temperature (15° to 30°C), and in an airtight container.
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