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Dolasetron Mesylate Injection - Indications, Dosage, Side Effects and Precautions

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Information about Dolasetron Mesylate Injection

Generic Name : Dolasetron Mesylate Injection
Up-to-date prescription details regarding Dolasetron Mesylate Injection are provided here.

Pronunciation : doh-LASS-eh-tron

Learn the correct pronunciation of the Dolasetron Mesylate Injection, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y43.0 Therapeutic Classification : Antiemetics

Trade Names/Brand Names of Dolasetron Mesylate Injection

International :


Anzemet

Why is Dolasetron Mesylate Injection Prescribed? (Indications)

This medication is a serotonin 5-HT3 receptor antagonist, prescribed for the prevention of nausea and vomiting associated with chemotherapy.  It blocks serotonin's action that may cause nausea and vomiting.

When should Dolasetron Mesylate Injection not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Dolasetron Mesylate Injection?

Adults- IV- The recommended dose is 1.8 mg/kg given as a single dose approximately 30 minutes before chemotherapy.

How should Dolasetron Mesylate Injection be taken?

It comes as a solution for injection, to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Dolasetron Mesylate Injection?

• Caution should be exercised in patients with history of heart problems, stomach or intestinal problems, kidney or liver disease, abnormal heart rhythm, who are taking other medications, any allergy, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• Avoid alcohol consumption.

What are the side effects of Dolasetron Mesylate Injection?

Body as a Whole - Headache, diarrhea, fever, fatigue, liver function abnormal, abdominal pain, high blood pressure, pain, dizziness, and chills/shivering.
Skin - Rash, increased sweating.
Gastrointestinal - Constipation, indigestion, abdominal pain, loss of appetite and inflammation of pancreas.
Eye and ENT - Taste perversion, abnormal vision, ringing in the ear and sensitivity to light.
Blood - Blood in urine, nosebleed, prolonged prothrombin time, PTT increased, anemia, purpura, blood clot, decrease in platelet counts.
Hypersensitivity - Anaphylactic reaction, swelling in the face, and hives.
Metabolic - Increased alkaline phosphatase level.
Musculoskeletal - Muscle pain, joint pain.
Central Nervous System - Flushing, fainting, tingling, tremor, incoordination, twitching, agitation, sleep disorder, depersonalization, confusion, anxiety and abnormal dreaming.
Respiratory - Difficulty in breathing and asthma.
Genitourinary - Painful urination, urinary frequency and acute kidney failure.

What are the other precautions for Dolasetron Mesylate Injection?

Avoid excess dosage.

What are the storage conditions for Dolasetron Mesylate Injection?

Store it at controlled room temperature (20-25°C). Protect from light.
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