Generic Name : Dofetilide Pronunciation : doe-FEH-till-ide Therapeutic Classification : Antiarrhythmics ICD Code : Y52.2
International- Tikosyn. Why it is prescribed (Indications) :
This medication is an antiarrhythmic agent, prescribed for irregular heart beat. It helps the heart to beat normally. When it is not to be taken (Contraindications):
Contraindicated in patients with severe kidney disease, long-term QT syndrome, co-administration with other medications and hypersensitivity.
Dosage & When it is to be taken :
Dose is based on creatinine clearance test. The recommended dose is 125 mcg once a day to 500 mcg twice a day. How it should be taken :
It comes as a capsule to take by mouth, with or without food. Warnings and Precautions :
* Caution should be exercised in patients with history of heart, liver or kidney disease, who are taking other medications, any allergy, during pregnancy and breastfeeding.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects :
Most Frequent- Headache, chest pain, rapid heart rhythm and dizziness.
Central Nervous System- Weakness, tingling and fainting.
Gastrointestinal- Nausea, vomiting, diarrhea and abdominal pain.
Respiratory - Respiratory tract infection, difficulty in breathing and increased cough.
Musculoskeletal- Joint/muscle pain, back pain and swelling of lower limbs.
Miscellaneous- Increased sweating, severe allergic reactions, stroke and liver damage.
* Patient may develop with increased risk of QT prolongation, if it so consult with your doctor.
Storage Conditions :
Store it at controlled room temperature (15° to 30°C), and in an airtight container. Keep away from children.
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