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Generic Name : Dofetilide
Pronunciation : doe-FEH-till-ide
Therapeutic Classification : Antiarrhythmics
ICD Code : Y52.2
Trade Name(s): International- Tikosyn. Why it is prescribed (Indications) : This medication is an antiarrhythmic agent, prescribed for irregular heart beat. It helps the heart to beat normally. When it is not to be taken (Contraindications): Contraindicated in patients with severe kidney disease, long-term QT syndrome, co-administration with other medications and hypersensitivity.
Dosage & When it is to be taken : Dose is based on creatinine clearance test. The recommended dose is 125 mcg once a day to 500 mcg twice a day. How it should be taken : It comes as a capsule to take by mouth, with or without food. Warnings and Precautions : * Caution should be exercised in patients with history of heart, liver or kidney disease, who are taking other medications, any allergy, during pregnancy and breastfeeding. * It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. * Avoid alcohol consumption. Side Effects : Most Frequent- Headache, chest pain, rapid heart rhythm and dizziness. Central Nervous System- Weakness, tingling and fainting. Gastrointestinal- Nausea, vomiting, diarrhea and abdominal pain. Respiratory - Respiratory tract infection, difficulty in breathing and increased cough. Musculoskeletal- Joint/muscle pain, back pain and swelling of lower limbs. Miscellaneous- Increased sweating, severe allergic reactions, stroke and liver damage. * Patient may develop with increased risk of QT prolongation, if it so consult with your doctor. Storage Conditions : Store it at controlled room temperature (15° to 30°C), and in an airtight container. Keep away from children. |
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