Dobutamine - Drug InformationGeneric Name : Dobutamine | Pronunciation : doe-BYOO-ta-meen
Why it is prescribed (Indications) :
This medication is a sympathomimetic compound used in the treatment of heart failure and cardiogenic shock. It stimulates the heart muscle.
When it is not to be taken (Contraindications):
Contraindicated in patients with hypersensitivity; idiopathic hypertrophic subaortic stenosis (Obstruction of the flow of blood out of the left ventricle due to enlargement of the ventricular septum), Tachydsrhythmias.
Pregnancy Category :
Category B :Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
Dosage & When it is to be taken :
Adult: IV -Acute heart failure- 2.5-10 mcg/kg, titrate to desired response.
Cardiac stress test- As 1 mg/mL solution: 5 mcg/kg/min for 8 minutes.
How it should be taken :
It comes as a solution for injection, to be injected by a healthcare provider into the vein.
Warnings and Precautions :Correct the decreased blood volume prior to treatment.
It may increase the risk of rapid ventricular response in patients with abnormal heart rate.
Caution needed for patients with history of liver disease, allergies, endocrine tumor, and irregular heartbeat/arrhythmia, hyperthyroidism, elderly, newborns, pregnancy.
Side Effects :
Heart- Increased heart rate and blood pressure, chest pain, palpitation.
Local- Inflammation of vein.
Miscellaneous- Nausea, vomiting, headache, anxiety, fatigue and shortness of breath
Potentially Fatal- Heart diseases.
Other Precautions :Monitor ECG, blood pressure regularly while taking this medication.
Avoid excess dosage.