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Generic Name : Disulfiram
Pronunciation : dye sul' fi ram
Therapeutic Classification : cholinergic agents
Trade Name(s):
India- Antadict, Chronol Tab, Deadict Tab, De-Quit Tab, Dfm Tab, Diabuse Tab, Disulfiram Tab, Esperal, Medibuse Tab, Nt-Addict Tab, Soberol, Sulfiram, Sufital, Tyfusin , Ulfiram. International- Antabuse. This medication is an alcohol antagonist, prescribed for chronic alcoholism. When it is not to be taken (Contraindications):
When it is to be taken : Adult: PO- 800 mg as a single dose on the 1st day. Reduce dose by 200 mg/day. Maintenance: 100-200 mg/day. How it should be taken : It comes as a tablet to take by mouth, with or without food. Special Instruction : * Caution should be exercised in patients with history of diabetes, thyroid disease, epilepsy, brain damage, kidney or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding. * It may cause drowsiness, do not drive a car or operate machinery while taking this medication. * Avoid alcohol consumption. * Monitor liver function and complete blood cell counts regularly while taking this medication. Side Effects : Eye inflammation, peripheral nerve disease, drowsiness, fatigue, impotence, headache and rash. * Avoid excess dosage. Storage Conditions : Store it at room temperature (20° to 25°C) and in an airtight container. Keep away from moisture and heat. |
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