Trade Names/Brand Names :
Why it is prescribed :
This medication (first-line oral treatment) is the methyl ester of fumaric acid, prescribed for multiple sclerosis.
When it is not to be taken (Contraindications):
Contraindicated in patients with known hypersensitivity.
Category C :
Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.
Dosage & When it is to be taken (Indications):
PO- The recommended initial dose is 120 mg twice a day, for 7 days.
How it should be taken :
It comes as a capsule to take by mouth, with or without food.
Warnings and Precautions :
• Caution should be exercised in patients with history of low white blood cell counts, any infection, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Side Effects :
• Most Common
Flushing, abdominal pain, diarrhea and nausea.
Decrease in white blood cells.
Abdominal pain, diarrhea, nausea, vomiting, indigestion.
Itching, rash, redness.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store at 15°C to 30°C.