Diflunisal - Drug Information

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General Information on Diflunisal

Generic Name : Diflunisal

Pronunciation : dye floo' ni sal

Latest prescription information about Diflunisal. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y45.1 | Therapeutic Classification : Analgesics

Trade Names/Brand Names of Diflunisal

International- Dolobid.

Why is Diflunisal Prescribed? (Indications)

This medication is a non-steroidal anti-inflammatory drug(NSAID), prescribed for rheumatoid arthritis, osteoarthritis and mild to moderate pain. This medication reduces the substances that cause pain and inflammation.  

When should Diflunisal not to be taken? (Contraindications)

Contraindicated in patients who have experienced asthma, hives, allergic reactions after taking aspirin or other NSAIDs, last 3 months pregnancy and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Diflunisal?

Initial: The recommended dose is 1000 mg followed by 500 mg every 12 hours. It may be reduced if needed.

How should Diflunisal be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Diflunisal?

Caution should be exercised in patients with history of high blood pressure, blood disorders, heart disease, kidney or liver disease, diabetes, stomach or bowel problems, any allergy, who are taking other medications, elderly, children, swelling of the hands, feet, ankles or lower legs, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid aspirin while taking this medication.
It should not be used in children with viral infections.
Monitor kidney function, complete blood cell counts and blood pressure regularly while taking this medication.

What are the side effects of Diflunisal?

   Gastrointestinal : Nausea, vomiting, indigestion, gastrointestinal pain, diarrhea, constipation and flatulence.
   Psychiatric : Drowsiness and sleeplessness.
   Central Nervous System : Dizziness.
   ENT : Ringing in the ear.
   Skin : Rash.
   Miscellaneous : Headache and fatigue/tiredness.

What are the other precautions for Diflunisal?

Avoid alcoholic beverages.
Avoid excess dosage.

What are the storage conditions of Diflunisal?

Store it at room temperature (15 -30o C), and in an airtight container. Keep away from children.

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