Generic Name : Didanosine Pronunciation : Dy-da-nose-in Therapeutic Classification : Antivirals ICD Code : Y41.5
India- Ddretro, Dinex-Ec, D-Sine, Retrodel-K, Virosine-D.
International- Videx EC. Why it is prescribed (Indications) :
This medication is a reverse transcriptase inhibitor, prescribed for HIV/AIDS either alone or with other antiretroviral drugs. It works by decreasing the amount of HIV in the blood. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
Daily dose is based on body weight.
Adult: PO- As tab/cap: patients with body weight more than 60kg: 400 mg/day. Patients with body weight less than 60 kg: 250 mg/day. How it should be taken :
It comes as a tablet to take by mouth, on en empty stomach. Warnings and Precautions :
* Caution should be exercised in patients with history of advanced HIV infection (AIDS), kidney, liver problems, gallstones, nerve problems, high blood cholesterol, any allergy, who are taking other medications, elderly, children especially less than 2 yeas old, during pregnancy and breastfeeding.
* Avoid alcohol consumption.
* It may cause severe side effects such as severe liver impairment, lactic acidosis in patients who are over weight, and in women. Those patients should consult with their doctor before taking this medication.
* Avoid sexual contact with your partner during the treatment to prevent the spread of HIV infection.
* Need to perform periodic eye exams.
* Monitor liver function, complete blood cell counts, and blood clotting while taking this medication. Side Effects :
Most Common - Inflammation of pancreas, diarrhea, nausea, vomiting, abdominal pain, headache, fatigue, rash, urea in blood, liver failure and blurred vision.
* Avoid excess dosage. Storage Conditions :
To be stored in a cool place and in an airtight container.
Comment & Contribute
Ask an Expert