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Generic Name : Dexmedetomidine
Pronunciation : dex-MED-e-TO-mi-dine HYE-droe-KLOR-ide
Therapeutic Classification : Sedative-hypnotic Drugs
ICD Code : Y47.8
Trade Name(s): India- Dexem inj. International- Precedex. Why it is prescribed (Indications) : This medication is a sedative, prescribed for intensive care unit sedation and procedural sedation. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken : Dosage is based on patient’s condition and response to the medication. IV: The recommended loading dose is 1mcg/kg over 10 minutes. Maintenance: 0.6mcg to 1mcg/kg/hr. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions : * A skilled person who has enough knowledge in handling intensive care unit patients should administer this medication. * Patient may develop with low heart rate, high blood pressure, sinus arrest, if it so either decrease the dosage or stop the medication. * Caution should be exercised in patients with history of heart diseases, decrease in blood volume, diabetes, chronic high blood pressure, elderly, during pregnancy and lactation. Side Effects : Most Common- Low blood pressure, slow heart rate and dry mouth. Body as a Whole - Fever, decreased blood volume, light anesthesia, pain and rigors. Heart- Blood pressure fluctuation, high/low blood pressure, heart attack, abnormal heart rhythm, fast/slow heart rate and dilation of blood vessels. Central Nervous System - Dizziness, headache, nerve pain/inflammation, speech disorder, convulsion, anxiety, agitation, confusion, hallucination and illusion. Gastrointestinal - Abdominal pain, diarrhea, vomiting, nausea and constipation. Liver- Increased level of liver enzymes and liver damage. Metabolic- Excess level of acid in blood, increased potassium level in blood and decrease/increase in sugar level. Blood- Anemia, easy bruising and bleeding. Genitourinary- Blood urea nitrogen increased and decreased urination. Respiratory - Asthma, shortness/poor breathing and lung obstruction. Skin - Increased sweating. Eye- Abnormal eye sensation and abnormal vision. *Take full course of treatment. Storage Conditions : Store it at controlled room temperature (25°C), and in an airtight container. |
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