Generic Name : Dexmedetomidine Pronunciation : dex-MED-e-TO-mi-dine HYE-droe-KLOR-ide Therapeutic Classification : Sedative-hypnotic Drugs ICD Code : Y47.8
India- Dexem inj.
International- Precedex. Why it is prescribed (Indications) :
This medication is a sedative, prescribed for intensive care unit sedation and procedural sedation. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
Dosage is based on patient’s condition and response to the medication.
IV: The recommended loading dose is 1mcg/kg over 10 minutes. Maintenance: 0.6mcg to 1mcg/kg/hr. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* A skilled person who has enough knowledge in handling intensive care unit patients should administer this medication.
* Patient may develop with low heart rate, high blood pressure, sinus arrest, if it so either decrease the dosage or stop the medication.
* Caution should be exercised in patients with history of heart diseases, decrease in blood volume, diabetes, chronic high blood pressure, elderly, during pregnancy and lactation.
Side Effects :
Most Common- Low blood pressure, slow heart rate and dry mouth.
Body as a Whole - Fever, decreased blood volume, light anesthesia, pain and rigors.
Heart- Blood pressure fluctuation, high/low blood pressure, heart attack, abnormal heart rhythm, fast/slow heart rate and dilation of blood vessels.
Central Nervous System - Dizziness, headache, nerve pain/inflammation, speech disorder, convulsion, anxiety, agitation, confusion, hallucination and illusion.
Gastrointestinal - Abdominal pain, diarrhea, vomiting, nausea and constipation.
Liver- Increased level of liver enzymes and liver damage.
Metabolic- Excess level of acid in blood, increased potassium level in blood and decrease/increase in sugar level.
Blood- Anemia, easy bruising and bleeding.
Genitourinary- Blood urea nitrogen increased and decreased urination.
Respiratory - Asthma, shortness/poor breathing and lung obstruction.
Skin - Increased sweating.
Eye- Abnormal eye sensation and abnormal vision.
*Take full course of treatment. Storage Conditions :
Store it at controlled room temperature (25°C), and in an airtight container.
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