Generic Name : Desirudin Pronunciation : deh-SIHR-uh-din Therapeutic Classification : Anticoagulants / Antithrombotics ICD Code : Y44.2
International- Revase, Iprivask. Why it is prescribed (Indications) :
This medication is a parenteral anticoagulant, prescribed for prophylaxis of deep vein thrombosis, which may lead to pulmonary embolism. It blocks the activity of thrombin, which helps in blood clot formation. When it is not to be taken (Contraindications):
Contraindicated in patients with active bleeding and hypersensitivity.
Dosage & When it is to be taken :
Adults - SC- 15 mg every 12 hour with the initial dose given up to 5 to 15 min before surgery, but after induction of regional block anesthesia if used. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into subcutaneous layer of the skin. Warnings and Precautions :
*Caution should be exercised in patients with stomach ulcer, sugar, liver or kidney disease, stroke, bleeding in the eyes, bacterial endocarditis, during pregnancy and breastfeeding.
* Administer only through subcutaneous method.
* Activated partial thromboplastin time should be monitored in patients with increased risk of bleeding.
* Monitor patient for signs of bleeding throughout therapy.
Side Effects :
Blood- Bleeding and blood clots.
Heart- Obstruction in blood circulation, low blood pressure and stroke.
Gastrointestinal- Nausea, vomiting and blood vomiting.
Miscellaneous- Injection site mass, pus, anemia, inflammation of veins, severe allergic reactions, swelling in the leg, fever, blood in urine, dizziness and nose bleed.
* Patient may develop with increased risk of developing an epidural or spinal blood clot, which can result in stroke.
Storage Conditions :
Store it at controlled room temperature (25o to 30oC), and in an airtight container.
Comment & Contribute
Ask an Expert