Deflazacort - Drug InformationGeneric Name : Deflazacort
International :Calcort, Cortax, Decortil, and Deflanil
Why it is prescribed (Indications) :
This medication is a glucocorticoid, prescribed for anti-inflammatory conditions, and used as an immunosuppressant. It is a prodrug.
When it is not to be taken (Contraindications):
Contraindicated in patients who are receiving immunosuppressive vaccines, who have infections and hypersensitivity.
Dosage & When it is to be taken :
Adult: PO- Initial: Up to 120 mg/day. Maintenance: 3-18 mg/day.
Child: Tablet: 0.25-1.5 mg/kg/day given on alternate days. Suspension: 5ml - 60ml per day.
How it should be taken :
It comes as a tablet, suspension and syrup to take by mouth, with food.
Warnings and Precautions :Caution should be exercised in patients with history of adrenal suppression, infections (ex- chickenpox , shingles , measles ) children, elderly, tuberculosis, muscle pain, recent heart attack, high blood pressure, heart failure, liver failure, kidney impairment, sugar, increased eye pressure, osteoporosis, corneal damage, epilepsy, peptic ulcer, under active thyroid, during pregnancy and breastfeeding.
Avoid long-term use of this medication and abrupt withdrawal.
Avoid contact with people with infections that can be spread to others.
Patients may develop with increased risk of confusion, irritability, nightmares, difficulty sleeping, mood changes and depression, and suffer from delusions and suicidal thoughts if it is taken excess; if it is so consult with your doctor.
Side Effects :
Metabolic - Increased blood sugar, increased appetite and weight gain.
Gastrointestinal - Indigestion, abdominal bloating, nausea, ulceration in the stomach or intestine, inflammation of the pancreas and throat ulcer.
Musculoskeletal - Muscle weakness and thinning of bones.
Skin - Pimples, bruising, stretch marks, increased sweating, change in pigmentation and increased hair growth.
Central Nervous System - Mood changes including irritability, depression and suicidal thoughts, psychotic reactions, anxiety, confusion, memory loss and sleep disturbances.
Genitourinary - Irregular periods.
Heart - High blood pressure.
Miscellaneous - Blood clot events and hiccups.