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Darifenacin

Updated on : January - 2012
Latest prescription information about Darifenacin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Darifenacin
Pronunciation : DAR-i-FEN-a-sin
Therapeutic Classification : Anticholinergics
ICD Code : Y51.3
Trade Name(s): 
India- Dariten, Vesigard, Xelena.
International- Enablex.
Why it is prescribed (Indications) : 
This medication is a muscarinic receptor antagonist, prescribed for overactive bladder with symptoms of urinary incontinence, urgency and frequency.  It relaxes bladder muscles to control urination.
When it is not to be taken (Contraindications): 
Contraindicated in patients with urinary retention, gastric retention, increased eye pressure, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
PO- Adult- The recommended starting dose is 7.5 mg once daily.
How it should be taken : 
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of stomach or intestinal problems, constipation, trouble emptying your bladder, weak urine stream, myasthenia gravis, increased eye pressure, liver impairment, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.
* It may cause heat stroke during hot weather.
Side Effects : 
Gastrointestinal - Dry mouth, constipation, indigestion, abdominal pain, nausea, and diarrhea.
Genitourinary - Urinary tract infection.
Central Nervous System - Dizziness, headache, confusion, hallucinations and somnolence.
Body As a Whole - Weakness.
Eye - Dry eyes.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C). Protect from light.
♦ Safety Labeling Changes Approved By FDA


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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