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Darbepoetin alfa

Latest prescription information about Darbepoetin alfa. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Darbepoetin alfa
Pronunciation : dar-be-POE-e-tin AL-fa al-BUE-min
Trade Name(s): 
India- Cresp.
International- Aranesp.
Why it is prescribed (Indications) : 
This medication is an erythropoiesis-stimulating agent, prescribed for anemia due to chronic kidney disease.

When it is not to be taken (Contraindications): 


Contraindicated in patients with uncontrolled high blood pressure, and known hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
SC/IV- The initial dose is 0.45 mcg/kg body weight, as a single injection once weekly.
For patients not receiving dialysis:
The initial dose is 0.75 mcg/kg as a single injection once every 2 weeks.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein or under the skin.
Special Instruction : 
* Caution should be exercised in patients with history of high blood pressure, heart disease, blood in stool, seizures, cancer, certain bone problem, blood disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Local - Injection site pain.
Body As A Whole - Swelling in the extremities, fatigue, fever, death, fluid retention, influenza-like symptoms, weakness and bleeding.
Heart - High or low blood pressure, abnormal heart rhythm, heart arrest, chest pain and heart failure.
Central Nervous System - Headache and dizziness.
Gastrointestinal - Diarrhea, vomiting, nausea, abdominal pain and constipation.
Musculoskeletal - Muscle spasm, joint pain, limb pain and back pain.
Respiratory - Upper respiratory tract infection, difficulty in breathing, cough and lung inflammation.
Skin - Itching.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature.

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