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Dapsone

Latest prescription information about Dapsone. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Dapsone
Pronunciation : DAP-sone
Therapeutic Classification : Antileprotics
ICD Code : Y41.1
Trade Name(s): 
India- Acnesone Gel, Dapsone Tab.
International- Aczone.
Other Name : DDS, diaminodiphenylsulfone.
Why it is prescribed (Indications) : 
This medication is an antibacterial drug, prescribed for leprosy and skin infections either alone or with other medications. It stops the bacterial growth.
When it is not to be taken (Contraindications): Contraindicated in patients with severe anemia and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult: PO- The recommended dose is 50 – 300mg/day.
How it should be taken : 
It comes as a tablet to take by mouth once a day or three times per week, without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of anemia, heart problems, blood disorder, urination problem, liver or kidney problems, high blood pressure, severe lung disease, any allergy, newborn, during pregnancy and breastfeeding.
* It may cause vision problem, dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* Avoid exposure to sunlight while taking this medication; otherwise it will lead to sunburn.
* Patient may develop with severe stomach pain or cramps, if it so consult with your doctor.
Side Effects : 
Most Common- Blurred vision, destruction of red blood cells, nausea, vomiting, loss of appetite, dizziness and sleeplessness.
Blood- Anemia, decreased albumin level in blood and increased white blood cells.
Central Nervous System- Numbness, weakness, burning pain (especially at night), headache, fainting and mental disorder.
Gastrointestinal- Abdominal pain, inflammation of pancreas.
Genitourinary- Protein/albumin in urine, kidney damage and male infertility.
Body As A Whole- Ringing in the ear, fever, skin damage due to excessive sunlight, fast heart rate and skin rash.
Other Precautions : 
* Take full course of treatment.
* Monitor blood counts, liver function regularly while taking this medication.
Storage Conditions : 
Store it at controlled room temperature (20°-25°C). Protect from light.


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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