Dantrolene - Drug Information

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General Information on Dantrolene

Generic Name : Dantrolene

Pronunciation : dan' troe leen

Latest prescription information about Dantrolene. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y55.1 | Therapeutic Classification : Skeletal Muscle Relaxants

Trade Names/Brand Names of Dantrolene

International- Dantrium.

Why is Dantrolene Prescribed? (Indications)

This medication is a muscle relaxant, prescribed for certain types of spasticity or muscle spasms. It works by relaxing the muscles.

When should Dantrolene not to be taken? (Contraindications)

Contraindicated in patients with severe liver impairment.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Dantrolene?

Adult- Po- The recommended dose range is 25-100mg, orally in divided doses.

How should Dantrolene be taken?

It comes as a capsule to take by mouth, with or without food.

What are the warnings and precautions for Dantrolene?

Caution should be exercised in patients with history of heart, lungs or liver problems, any allergy, who are taking other medications, elderlyduring pregnancy and breastfeeding.
It may cause dizziness, drowsiness or lightheadedness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.

What are the side effects of Dantrolene?

   Gastrointestinal : Constipation, GI bleeding, loss of appetite, difficulty in swallowing, gastric irritation, abdominal cramps, nausea and vomiting.
   Liver : Liver inflammation.
   Central Nervous System : Speech disturbances, seizures, headache, lightheadedness, visual disturbances, double vision, alteration of taste and sleeplessness.
   Heart : Fast heart rate, erratic blood pressure and vein inflammation, heart failure .
   Psychiatric : Mental depression, mental confusion and nervousness.
   Genitourinary : Increased urinary frequency, blood in urine, difficult erection, urinary incontinence, difficult urination and/or urinary retention.
   Skin : Abnormal hair growth, acne-like rash, itching, hives, eruption and increased sweating.
   Musculoskeletal : Muscle pain and backache.
   Respiratory : Feeling of suffocation and respiratory depression.
   Eye and ENT : Excessive tearing.
   Hypersensitivity : Lung infection.
  Blood: Anemia, leukopenia, lymphocytic lymphoma, thrombocytopenia.
   Miscellaneous : Chills and fever.

What are the other precautions for Dantrolene?

Avoid excess dosage.

What are the storage conditions of Dantrolene?

Keep this medication in the container it came in, tightly closed and out of the reach of children. Store it at room temperature.

♦ Safety Labeling Changes Approved By FDA

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