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Dactinomycin
Latest prescription information about Dactinomycin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Dactinomycin
Pronunciation : dak ti noe mye' sin
Therapeutic Classification : Chemotherapy
Trade Name(s):
India- Cosmegen Vial, Dacilon Inj , Dacmozen Antineoplastic Vial, Dactino Vial. International- Cosmegen. This medication is a cytotoxic chemotherapy, prescribed for Wilm's tumor, Ewing’s sarcoma and testicular cancer. This medication slows the growth and spread of cancer cells in the body. When it is not to be taken (Contraindications):
When it is to be taken : Adult: IV- Wilm's tumor; Ewing's sarcoma; Childhood rhabdomyosarcoma- 15 mcg/kg/day for 5 days in combination regimens. Gestational trophoblastic tumours- 12 mcg/kg/day for 5 days as a single agent. Metastatic nonseminomatous testicular cancer- 1 mg/m2 on day 1 of combination regimens. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Special Instruction : * Caution should be exercised in patients with history of bone marrow problems, obesity, radiation therapy, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. * It may cause nausea, vomiting or loss of appetite, if it so consult with your doctor. * This medication may reduce platelet counts, avoid injury or bruising. Side Effects : Miscellaneous - Uneasiness, fatigue, lethargy, fever, muscle pain, inflammation of the rectum, decreased calcium level in blood, growth retardation and infection. Lung - Lung inflammation. Gastrointestinal - Loss of appetite, indigestion, nausea, vomiting, abdominal pain, diarrhea, gastrointestinal ulceration, mouth ulcer and inflammation of esophagus. Liver - Liver toxicity. Blood - Anemia and decrease in blood counts. Skin - Hair loss, skin eruptions, pimples and redness. * Avoid vaccination during therapy. * Monitor liver function, kidney function and blood counts regularly while taking this medication. Storage Conditions : Intravenous: Store it at room temperature (25°C). |
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