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Daclizumab

Latest prescription information about Daclizumab. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Daclizumab
Pronunciation : (da-kliz-uh-mab)
Therapeutic Classification : Immunosuppressants
ICD Code : Y43.4
Trade Name(s): 
International- Zenapax.
Why it is prescribed (Indications) : 
This medication is an immunosuppressive agent, prescribed for acute organ rejection during kidney transplantation.  
When it is not to be taken (Contraindications): 
Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
IV- The recommended dose in adult and pediatric patients is 1mg/kg.
How it should be taken : 
It comes as a solution for injection to be administered by a health care provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with any allergy, during pregnancy and breastfeeding.
* It may cause dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.
* It may affect blood sugar level; monitor sugar level regularly while taking this medication.
Side Effects : 
Gastrointestinal - Constipation, nausea, diarrhea, vomiting, abdominal pain, indigestion, abdominal distention and abdominal pain.
Metabolic - Swelling in the extremities.
Central Nervous System - Tremor, headache, sleeplessness and dizziness.
Genitourinary - Painful urination and kidney damage.
Body as a Whole - Post-traumatic pain, chest pain, fever, pain and fatigue.
Heart - High blood pressure and fast heart rate.
Respiratory - Difficulty in breathing, lung swelling and increased cough.
Skin - Impaired wound healing without infection and pimples.
Musculoskeletal - Musculoskeletal pain and back pain.
Blood - Decrease in platelet count and bleeding disorders.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2° to 8°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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