Generic Name : Dacarbazine Pronunciation : da kar' ba zeen
Therapeutic Classification : Chemotherapy Trade Name(s):
India- Arzi Vial, Celdaz Inj, Dabaz Vial , Dacarba Vial , Dacarex Vial , Dacarin Vial, Dacarzine Vial, Daczin Vial, Decarb Vial, and Oncodac Vial.
International- DTIC-Dome. Why it is prescribed (Indications) :
This medication is an antineoplastic chemotherapy drug, prescribed for melanoma and Hodgkin's disease. This medication slows the growth and spread of cancer cells in the body. When it is not to be taken (Contraindications):
Contraindicated in patients with bone marrow suppression and hypersensitivity.
Dosage & When it is to be taken :
Malignant Melanoma: The recommended dosage is 2 to 4.5mg/kg/day for 10 days. Treatment may be repeated at 4-week intervals.
Hodgkin's Disease: The recommended dose is 150mg/square meter body surface/day for 5 days. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* Avoid drinking alcoholic beverages and citrus fruit juices. Side Effects :
Most Common - Nausea, vomiting, diarrhea and loss of appetite.
Miscellaneous - Hair loss, tingling, photosensitivity, rashes and facial flushing.
Liver - Liver damage.
* Avoid excess dosage. Storage Conditions :
Store it in refrigerator (2-8°C). Do not freeze it.
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