Cyclosporine - Drug Information

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General Information on Cyclosporine

Generic Name : Cyclosporine

Pronunciation : sye' kloe spor een

Latest prescription information about Cyclosporine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.4 | Therapeutic Classification : Immunosuppressants

Why is Cyclosporine Prescribed? (Indications)

This medication is an immunosuppressant, prescribed for prevention of organ rejection during transplantation. It is also used for psoriasis, rheumatoid arthritis, and uveitis.  It works by suppressing the immune system.

When should Cyclosporine not to be taken? (Contraindications)

Hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Cyclosporine?

Adult- PO- The recommended initial dose range is 10 to 15mg/kg/day. Maintenance: 2 to 6mg/kg/day.

How should Cyclosporine be taken?

It comes as a capsule and suspension to take by mouth. It also comes as a solution for injection to be administered by a healthcare provider into the vein. It also comes as eye drops to instill into the affected eyes.

What are the warnings and precautions for Cyclosporine?

Caution should be exercised in patients with liver, kidney, brain or nerve problems, changes in blood mineral and cholesterol levels, high blood pressure, cancer, gout, infection, recent vaccination, any allergy, who are taking other medications, during pregnancy and breast feeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Patient may develop with increased risk of Nephrotoxicity, skin cancer; wear protective clothing during outdoors.
Avoid vaccination during the treatment period.
This medication may reduce platelet counts; avoid injury or bruising.
Avoid eating Grapefruit or drinking Grapefruit juice while taking this medication.

What are the side effects of Cyclosporine?

   Most Common : Kidney dysfunction, tremor and high blood pressure.
   Heart : Cramps.
   Skin : Abnormal growth of hair over the body surface.
   Central Nervous System : Convulsions and headache.
   Gastrointestinal : Overgrowth of gums, diarrhea, nausea/vomiting, liver damage and abdominal discomfort.
   Autonomic Nervous System : Tingling and flushing.
   Blood : Decrease in white blood cells and cancer in lymph nodes.
   Respiratory : Sinusitis.
   Miscellaneous : Breast enlargement in males.

What are the other precautions for Cyclosporine?

Monitor blood sugar regularly while taking this medication.

What are the storage conditions of Cyclosporine?

Store it at room temperature (25C), and in an airtight container.

♦ Safety Labeling Changes Approved By FDA

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sam1956 

my question is : for the medication [ Sandimmun-Neoral ] 100 mg What is content of the soft gelatine capsules ( does it contain pork ? ) Please advise I have taken this medication and develop Nausea , abdominal pain , allergic skin reactions , mental confusion, insomnia, hyper tension , muscle cramps and weakness , tremor , headache, convulsions , shortness breath , palpitation, numbness, This medication is prescribed for me from dermatologist doctor as am suffering from chronic urticaria please advise

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