Generic Name : Cycloserine Pronunciation : sigh-kloe-SER-een Therapeutic Classification : Anti- Tuberculosis ICD Code : Y41.1
India- MDSerine, Pamserine, Cyclorin, Novaserine, Cyclorine, Coxerin, Myser, Cyserin, Cyclokox.
International- Seromycin. Why it is prescribed (Indications) :
This medication is an antibiotic, prescribed for tuberculosis (TB). It is also used to treat certain urinary tract infections. It stops or slows the growth of bacterial cells. When it is not to be taken (Contraindications):
Contraindicated in patients with severe kidney impairment, porphyria, depression, epilepsy, severe anxiety, psychosis, chronic alcoholism, and hypersensitivity.
Dosage & When it is to be taken :
PO- With other drugs: Initial: 250 mg twice daily for 2 wk, increase to 0.5-1 gm/day in divided doses. Max: 1 gm/day. How it should be taken :
It comes as a tablet or capsule to take by mouth, with or without food. Warnings and Precautions :
* Caution should be exercised in patients with history of anxiety, kidney or liver disease, blood disorder, alcoholism, any allergy, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* Avoid long-term use of this medication; otherwise it may cause secondary infection.
* Monitor complete blood cell counts, kidney and liver function, and cycloserine level in blood regularly while taking this medication. Side Effects :
Central Nervous System - Headache, dizziness, anxiety, confusion, irritability, tingling, speech difficulties, fainting, drowsiness, tremor, psychosis and depression.
Miscellaneous - Sensitivity to light, rash, anemia and changes in liver function tests.
* Avoid excess dosage. Storage Conditions :
Store it at room temperature.
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