Medindia » Medication Manual » Cyclobenzaprine

Cyclobenzaprine

Latest prescription information about Cyclobenzaprine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Cyclobenzaprine
Pronunciation : sye kloe ben' za preen
Therapeutic Classification : Skeletal Muscle Relaxants
ICD Code : Y55.1
Trade Name(s): 
India- Mobrine-IR tab.
International- Flexeril.
Why it is prescribed (Indications) : 
This medication is a skeletal muscle relaxant, prescribed for pain and stiffness caused by muscle strains and sprains. It works by blocking nerve impulses.
When it is not to be taken (Contraindications): 
Contraindicated in patients who are taking Monoamine Oxidase Inhibitors(MAOIs) or within 14 days after discontinuation, an overactive thyroid, moderate to severe liver problems, certain heart problems and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
PO- The recommended dose is one (15 mg) capsule or tablet, once daily.
How it should be taken : 
It comes as a tablet and capsule to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of overactive thyroid, heart disease, increased eye pressure, difficulty in urinating, liver problems, cerebral palsy, brain or spinal cord disease, stroke, any allergy, who are taking other medications, elderly, children, during pregnancy and breast feeding.
* It may cause drowsiness, dizziness or blurred vision, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* It may cause heat stroke, maintain your body in cool.
Side Effects : 
Most Common - Drowsiness, headache, dizziness, blurred vision, nausea, abnormal taste, palpitations, tremor, dry throat, pimples, attention disturbances, sleeplessness, fatigue, constipation and indigestion.
Body as a Whole - Fainting and uneasiness.
Heart - Fast heart rate, dilatation of blood vessels and low blood pressure.
Gastrointestinal - Vomiting, loss of appetite, diarrhea, gastrointestinal pain, thirst, flatulence, swelling of the tongue, abnormal liver function tests and jaundice.
Hypersensitivity - Itching, facial swelling, hives and rash.
Musculoskeletal - Local weakness.
Central Nervous System - Seizures, incoordination, speech disorder, tremors, increased muscle tone, convulsions, muscle twitching, disorientation, depressed mood, abnormal sensations, anxiety, agitation, abnormal thinking and dreaming, hallucinations, excitement and tingling.
Skin - Increased sweating.
Special Senses - Loss of taste and ringing in the ear.
Genitourinary - Urinary frequency and retention.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature and in an airtight container. Keep away from children.


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Posted by:  rosy_jatinder, Canada  Posted on: 4/1/2013
Take this medication only with food and at bedtime. Drink enough water and specially more water if u feel drowsiness when u wake up next morning.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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