Co-trimoxazole - Drug Information

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General Information on Co-trimoxazole

Generic Name : Co-trimoxazole

Pronunciation : coe try mox' a zole

Latest prescription information about Co-trimoxazole. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.8 | Therapeutic Classification : Anti- Infectives

Why is Co-trimoxazole Prescribed? (Indications)

This medication is a combination of trimethoprim and sulfamethoxazole, prescribed for certain types bacterial infections. It is also used to treat traveler’s diarrhea.  It eliminates bacteria that cause various infections.

When should Co-trimoxazole not to be taken? (Contraindications)

Contraindicated in patients with anemia, hypersensitivity, during pregnancy and breast-feeding.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Co-trimoxazole?

It is a fixed combination product containing sulfamethoxazole and trimethoprim in 5:1 ratio.
Adult- PO- The recommended dose is 2 tablets every 12 hours for a period of 10 to 14 days.
Child- The recommended dose is 8 mg/kg of trimethoprim and 40 mg/kg of sulfamethoxazole daily in 2 divided doses every 12 hours.

How should Co-trimoxazole be taken?

It comes as a tablet and liquid to take by mouth, with or without food.

What are the warnings and precautions for Co-trimoxazole?

• Caution should be exercised in patients with history of liver or kidney disease, asthma, severe allergies, glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease), any allergy, who are taking other medications.
• Avoid exposure to sunlight.

What are the side effects of Co-trimoxazole?

   Most Common : Nausea, vomiting and loss of appetite.
   Blood : Decrease in blood cell counts.
   Allergic : Skin inflammation, eruptions, rash, itching, redness, hives, bruising and photosensitivity.
   Gastrointestinal : Liver inflammation/damage, jaundice, hepatic necrosis, elevation in liver enzymes, inflammation of intestine/pancreas/tongue, mouth ulcer, abdominal pain and diarrhea.
   Genitourinary : Kidney failure, Blood Urea Nitrogen and absence of urination.
   Central Nervous System : Brain inflammation, convulsions, incoordination, fainting, ringing in the ear, headache, hallucinations, depression and nervousness.
   Metabolic : Low blood sugar.
   Musculoskeletal : Joint/muscle pain.
   Respiratory : Cough, shortness of breath and lung infection.
   Miscellaneous : Weakness, fatigue and sleeplessness.

What are the other precautions for Co-trimoxazole?

Avoid excess dosage.

What are the storage conditions of Co-trimoxazole?

Store it at controlled room temperature (15–25°C), protect from light.

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dulce 

i want to ask only if this medicine, same as ultramox 500mg. cause i take cotrimoxazole for the mine time,

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