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Generic Name : Co-trimoxazole
Pronunciation : coe try mox' a zole
Trade Name(s):
India- Intrim, Intrim D S, Monatrim. International- Bactrim, Bactrim DS, Septra, Septra DS, Sulfatrim. This medication is a combination of trimethoprim and sulfamethoxazole, prescribed for certain types bacterial infections. It is also used to treat traveler’s diarrhea. When it is not to be taken (Contraindications):
When it is to be taken : It is a fixed combination product containing sulfamethoxazole and trimethoprim in 5:1 ratio. Adult- PO- The recommended dose is 2 tablets every 12 hours for a period of 10 to 14 days. Child- The recommended dose is 8 mg/kg of trimethoprim and 40 mg/kg of sulfamethoxazole daily in 2 divided doses every 12 hours. How it should be taken : It comes as a tablet and liquid to take by mouth, with or without food. Special Instruction : * Caution should be exercised in patients with history of liver or kidney disease, asthma, severe allergies, glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease), any allergy, who are taking other medications. * Avoid exposure to sunlight. Side Effects : Most Common - Nausea, vomiting and loss of appetite. Blood - Decrease in blood cell counts. Allergic - Skin inflammation, eruptions, rash, itching, redness, hives, bruising and photosensitivity. Gastrointestinal - Liver inflammation/damage, jaundice, hepatic necrosis, elevation in liver enzymes, inflammation of intestine/pancreas/tongue, mouth ulcer, abdominal pain and diarrhea. Genitourinary - Kidney failure, Blood Urea Nitrogen and absence of urination. Central Nervous System - Brain inflammation, convulsions, incoordination, fainting, ringing in the ear, headache, hallucinations, depression and nervousness. Metabolic - Low blood sugar. Musculoskeletal - Joint/muscle pain. Respiratory - Cough, shortness of breath and lung infection. Miscellaneous - Weakness, fatigue and sleeplessness. *Avoid excess dosage. Storage Conditions : Store it at controlled room temperature (15–25°C), protect from light. |
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