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Generic Name : Conivaptan
Pronunciation : KOE-ni-VAP-tan
Therapeutic Classification : Cardiovascular Agents
ICD Code : Y52
Trade Name(s): International- Vaprisol. Why it is prescribed (Indications) : This medication is an arginine vasopressin receptor antagonist, prescribed for hyponatremia (low blood sodium level). When it is not to be taken (Contraindications): Contraindicated in patients with anuria (absence of urination), severe kidney problems who are taking CYP3A inhibitors, electrolyte disturbances, and hypersensitivity.
Dosage & When it is to be taken : Adults- Euvolemic or Hypervolemic Hyponatremia: IV- Initially, 20 mg as a loading dose over 30 minutes, followed by continuous infusion of 20 mg over 24 hours for 2–4 days. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions : * Caution should be exercised in patients with history of heart failure, liver, or kidney problems, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding. * It may cause dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication. * It may affect blood sugar level; monitor sugar level regularly while taking this medication. Side Effects : Blood - Anemia. Heart - Abnormal heart rhythm and high/low blood pressure. Gastrointestinal - Constipation, diarrhea, nausea and vomiting. General - Swelling in the extremities, injection site reactions such as redness, pain, inflammation, fever and thirst. Infections - Pneumonia and urinary tract infection. Metabolic - Decrease in blood minerals. Central Nervous system - Headache, confusion and sleeplessness. Respiratory - Throat pain. Skin - Itching. * Avoid excess dosage. Storage Conditions : Normally handled and stored by a health care provider. |
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