Generic Name : Conivaptan Pronunciation : KOE-ni-VAP-tan Therapeutic Classification : Cardiovascular Agents ICD Code : Y52
International- Vaprisol. Why it is prescribed (Indications) :
This medication is an arginine vasopressin receptor antagonist, prescribed for hyponatremia (low blood sodium level). When it is not to be taken (Contraindications):
Contraindicated in patients with anuria (absence of urination), severe kidney problems who are taking CYP3A inhibitors, electrolyte disturbances, and hypersensitivity.
Dosage & When it is to be taken :
Adults- Euvolemic or Hypervolemic Hyponatremia: IV- Initially, 20 mg as a loading dose over 30 minutes, followed by continuous infusion of 20 mg over 24 hours for 2–4 days. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of heart failure, liver, or kidney problems, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
* It may affect blood sugar level; monitor sugar level regularly while taking this medication. Side Effects :
Blood - Anemia.
Heart - Abnormal heart rhythm and high/low blood pressure.
Gastrointestinal - Constipation, diarrhea, nausea and vomiting.
General - Swelling in the extremities, injection site reactions such as redness, pain, inflammation, fever and thirst.
Infections - Pneumonia and urinary tract infection.
Metabolic - Decrease in blood minerals.
Central Nervous system - Headache, confusion and sleeplessness.
Respiratory - Throat pain.
Skin - Itching.
* Avoid excess dosage. Storage Conditions :
Normally handled and stored by a health care provider.
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