Medindia » Medication Manual » Conivaptan

Conivaptan

Updated on : February - 2012
Latest prescription information about Conivaptan. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Conivaptan
Pronunciation : KOE-ni-VAP-tan
Therapeutic Classification : Cardiovascular Agents
ICD Code : Y52
Trade Name(s): 
International- Vaprisol.
Why it is prescribed (Indications) : 
This medication is an arginine vasopressin receptor antagonist, prescribed for hyponatremia (low blood sodium level). 
When it is not to be taken (Contraindications): 
Contraindicated in patients with anuria (absence of urination), severe kidney problems who are taking CYP3A inhibitors, electrolyte disturbances, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adults- Euvolemic or Hypervolemic Hyponatremia: IV- Initially, 20 mg as a loading dose over 30 minutes, followed by continuous infusion of 20 mg over 24 hours for 2–4 days.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart failure, liver, or kidney problems, alcoholism, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
* It may affect blood sugar level; monitor sugar level regularly while taking this medication.
Side Effects : 
Blood - Anemia.
Heart - Abnormal heart rhythm and high/low blood pressure.
Gastrointestinal - Constipation, diarrhea, nausea and vomiting.
General - Swelling in the extremities, injection site reactions such as redness, pain, inflammation, fever and thirst.
Infections - Pneumonia and urinary tract infection.
Metabolic - Decrease in blood minerals.
Central Nervous system - Headache, confusion and sleeplessness.
Respiratory - Throat pain.
Skin - Itching.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Normally handled and stored by a health care provider.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z