Generic Name : Collagenase Clostridium Histolyticum Pronunciation : COL-a-geh-nase klo-STRID-ee-um his-toe-LIT-ik-um Therapeutic Classification : Enzymes ICD Code : Y43.6
International- Xiaflex. Why it is prescribed (Indications) :
This medication is a collagenase enzyme, prescribed for dupuytren contracture (condition that affects the hands and fingers). It works by breaking collagen in the cord, which allows the fingers to straighten. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken :
The recommended dose 0.58 mg per injection. How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the palpable cord with a contracture of a metacarpophalangeal (MP) joint or a proximal interphalangeal (PIP) joint. Warnings and Precautions :
*Caution needed for pregnant and breastfeeding women, and in patients with bleeding problems. Side Effects :
Swelling of the injected hand, bruise, injection site bleeding, injection site reaction, and pain in the treated extremity.
* Avoid excess dosage. Storage Conditions :
Store it in a refrigerator at 2° to 8°C.
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