Medindia » Medication Manual » Cobicistat-Elvitegravir-Emtricitabine-Tenofovir

Cobicistat-Elvitegravir-Emtricitabine-Tenofovir

Latest prescription information about Cobicistat-Elvitegravir-Emtricitabine-Tenofovir. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Cobicistat-Elvitegravir-Emtricitabine-Tenofovir
Trade Name(s): 
International- Stribild.
Why it is prescribed (Indications) : This combination medication contains integrase strand transfer inhibitor, pharmacokinetic enhancer and nucleos(t)ide analog HIV-1 reverse transcriptase inhibitors, prescribed for HIV-1 infection. 
When it is not to be taken (Contraindications): It should not be co-administered with highly CYP3A dependents.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : PO- The recommended dose is one tablet once daily.
How it should be taken : It comes as a tablet to take by mouth, with food.
Warnings and Precautions : 
* Monitor bone mineral density (BMD), creatinine clearance (CrCl), urine glucose, and urine protein regularly while taking this medication.
* Redistribution or accumulation of body fat may occur; if it is so consult with your doctor
Side Effects : 
Most Common - Nausea and diarrhea.
Eye - Ocular icterus.
Gastrointestinal - Diarrhea, flatulence, nausea.,
Central Nervous System - Fatigue, drowsiness, headache, dizziness, sleeplessness, abnormal dreams.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store the medication as directed by your physician.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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