Clomipramine - Drug Information

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General Information on Clomipramine

Generic Name : Clomipramine

Pronunciation : kloe mi' pra meen

Latest prescription information about Clomipramine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y49.0 | Therapeutic Classification : Psychotherapeutics

Why is Clomipramine Prescribed? (Indications)

This medication is a tricyclic antidepressant (TCA), prescribed for obsessive-compulsive disorder.  It increases the amount of serotonin that needs to maintain mental balance.

When should Clomipramine not to be taken? (Contraindications)

Contraindicated in patients with recent heart attack, hypersensitivity and it should not be given in combination, or within 14 days before or after treatment, with a monoamine oxidase (MAO) inhibitor, Who are taking linezolid or intravenous methylene blue.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Clomipramine?

Adult- Oral- The recommended dose range is 25 to 150mg/day.

How should Clomipramine be taken?

It comes as a tablet and capsule to take by mouth, with food.

What are the warnings and precautions for Clomipramine?

Caution should be exercised in patients with history of seizures, brain damage, urinary problems, increased eye pressure, irregular heartbeat, high blood pressure, thyroid problems, heart, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast feeding.
It may cause drowsiness, dizziness or blurred vision, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Avoid abrupt withdrawal; withdraw gradually.
Avoid alcohol consumption.
Avoid becoming overheated in hot weather; otherwise it may cause heatstroke.
It may develop an increased risk of suicidal thoughts in children and teenagers; watch them carefully.
Avoid exposure to sunlight; otherwise it may lead to sunburn.

What are the side effects of Clomipramine?

   Body as a Whole : Fatigue, increased or decreased weight, flushing, chest pain, fever, chills, allergy and weakness.
   Central Nervous System : Dizziness, lightheadedness, faintness, nervousness, tiredness, confusion, difficulty in sleeping, decreased sexual ability, decreased memory or concentration, headache, speech disorder and emotional lability.
   Gastrointestinal : Dry mouth, constipation, diarrhea, indigestion, loss of appetite, abdominal pain, tooth disorder, difficulty in swallowing, nausea and vomiting.
   Heart : Low blood pressure, palpitation, fast heart rate and fainting.
   Respiratory : Inflammation of upper respiratory tract, cough, asthma and difficulty in breathing.
   Genitourinary:Common- Urinating disorder, urinary tract infection, urinary frequency/retention, painful urination and bladder inflammation.
   Female: Painful menstrual period, vaginal inflammation, absence of menstrual period, breast pain and white discharge.
   Male: Impotence.
   Eye and ENT : Abnormal vision, taste perversion, ringing in the ear, dilatation of pupil, unequal size of the pupils.
   Musculoskeletal : Muscle/joint pain, back pain and muscle weakness.
   Blood : Anemia and bruising.
   Metabolic : Increased thirst.

What are the other precautions for Clomipramine?

Do not allow anyone else to take this medication.

What are the storage conditions of Clomipramine?

Store it at room temperature and away from moisture.

♦ Safety Labeling Changes Approved By FDA

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narasimhapotla 

I have been taking clonal 25 mg tablet but I am getting too much sedation even though after 8 hours and upto 20 hours may I know how to over come and also along with arip 7.5 mg sometimes but same problem and restlessness, energy lessens cant tosleep and cant to do any thing may I know what I have to do.

Rembrandt49 

I have been taking clonil25 for last eight years. I tried discontinuing it in tapering doses. Was successful for a few months. But the problem returned with vengeance . I had to resume taking it. Does it mean I shall be dependent on it lifelong?

fesvy 

Does clonil make a man impotent?

Davie 

why cant i get anafranil in the United Kingdom anymore

hiteshbabbar 

sir, i am taking clonil 25 mg for the past 2-3 years but now i have a problem of urinating what
also my body weight increased (body weight is not a problem but extreme urinating is problem)
please suggest what to do

View all Comments (18)
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