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Clomipramine

Updated on : October - 2012
Latest prescription information about Clomipramine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Clomipramine
Pronunciation : kloe mi' pra meen
Therapeutic Classification : Psychotherapeutics
ICD Code : Y49.0
Trade Name(s): 
India- Anafranil Tab, Clofranil Sr-Tab, Clofranil Tab, Clomine Tab, Clomip Tab, Clomistar Sr-Tab, Clomistar Tab, Clomizil Cap, Clom-Sr Sr-Tab, Clonil Sr-Tab, Clonil Tab, Depnil Tab, Mario Tab, Ocifril Film-Coated Tab, Ocifril-Xr Film-Coated Tab, Syconil Film-Coated Tab.
International- Anafranil.
Why it is prescribed (Indications) : This medication is a tricyclic antidepressant (TCA), prescribed for obsessive-compulsive disorder.  It increases the amount of serotonin that needs to maintain mental balance.
When it is not to be taken (Contraindications):  Contraindicated in patients with recent heart attack, hypersensitivity and it should not be given in combination, or within 14 days before or after treatment, with a monoamine oxidase (MAO) inhibitor, Who are taking linezolid or intravenous methylene blue.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : Adult- Oral- The recommended dose range is 25 to 150mg/day.
How it should be taken : It comes as a tablet and capsule to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of seizures, brain damage, urinary problems, increased eye pressure, irregular heartbeat, high blood pressure, thyroid problems, heart, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast feeding.
* It may cause drowsiness, dizziness or blurred vision, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
* Avoid abrupt withdrawal; withdraw gradually.
* Avoid alcohol consumption.
* Avoid becoming overheated in hot weather; otherwise it may cause heatstroke.
* It may develop an increased risk of suicidal thoughts in children and teenagers; watch them carefully.
* Avoid exposure to sunlight; otherwise it may lead to sunburn.
Side Effects : 
Body as a Whole - Fatigue, increased or decreased weight, flushing, chest pain, fever, chills, allergy and weakness.
Central Nervous System - Dizziness, lightheadedness, faintness, nervousness, tiredness, confusion, difficulty in sleeping, decreased sexual ability, decreased memory or concentration, headache, speech disorder and emotional lability.
Gastrointestinal - Dry mouth, constipation, diarrhea, indigestion, loss of appetite, abdominal pain, tooth disorder, difficulty in swallowing, nausea and vomiting.
Heart - Low blood pressure, palpitation, fast heart rate and fainting.
Respiratory - Inflammation of upper respiratory tract, cough, asthma and difficulty in breathing.
Genitourinary-Common- Urinating disorder, urinary tract infection, urinary frequency/retention, painful urination and bladder inflammation.
Female: Painful menstrual period, vaginal inflammation, absence of menstrual period, breast pain and white discharge.
Male: Impotence.
Eye and ENT - Abnormal vision, taste perversion, ringing in the ear, dilatation of pupil, unequal size of the pupils.
Musculoskeletal - Muscle/joint pain, back pain and muscle weakness.
Blood - Anemia and bruising.
Metabolic - Increased thirst.
Other Precautions : 
* Do not allow anyone else to take this medication.
Storage Conditions : 
Store it at room temperature and away from moisture.
♦ Safety Labeling Changes Approved By FDA

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Member Comments ( 14 )
sir, i am taking clonil 25 mg for the past 2-3 years but now i have a problem of urinating what
also my body weight increased (body weight is not a problem but extreme urinating is problem)
please suggest what to do

(Posted by hiteshbabbar, India Date : 2/28/2011 )
I AM TAKING CLONILSR75 AND UVOX 50MG FOR DISEASE PHOBIA OCD WHEN I STOP TAKING THIS DRUG DISEASE STARTS AGAIN
(Posted by monty, India Date : 9/26/2010 )
I am taking Fluvoxin 100 mg and Clonil 50 mg and 20 mg Rexipra for ocd, I am suffering from ocd from 3 years, am in a good treatment?
(Posted by madhumithaaaaaaaaaa, India Date : 9/18/2010 )
I was taking clonil-25 b4 5yrs due to OCD,but as tme passes i succeeded to stp it completely due to recovery.....bt nw again i have been suggested to start at 1 time a day,
does it makes weak or causes loose muscles and vibration in fingers....?????

(Posted by karan_x, India Date : 1/2/2010 )
I have been using clofranil 50mg for the past 7 years .I wish to quit the drug now.Present age 29
(Posted by somesh, India Date : 12/3/2009 )
View All Comments (14)

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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