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Clofazimine - Indications, Dosage, Side Effects and Precautions

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Information about Clofazimine

Generic Name : Clofazimine
Up-to-date prescription details regarding Clofazimine are provided here.

Pronunciation : kloe-FAZ-i-meen

Learn the correct pronunciation of the Clofazimine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y41.1 Therapeutic Classification : Antileprotics

Trade Names/Brand Names of Clofazimine

India :

International :


Lamprene

Why is Clofazimine Prescribed? (Indications)

This medication is an anti-inflammatory agent, prescribed for leprosy with other drugs. It is also used to treat reactions to anti – leprosy drugs.

When should Clofazimine not be taken? (Contraindications)

Hypersensitivity, lactation.

What is the dosage of Clofazimine?

Multibacillary Leprosy treatment: 50 mg daily plus 300 mg once a month along with other antileprosy drugs for 1 year.
Reactions in Leprosy: Treatment depends on severity. 100-200 mg/day for up to 3 month.

How should Clofazimine be taken?

It comes as a capsule to take by mouth once a day, with or without food.

What are the warnings and precautions for Clofazimine?

•It may cause dizziness, drowsiness. Do not drive a car or operate machinery while taking this medication.

• It may cause a red to brownish black discoloration of skin, mucous membranes and secretions.

• Avoid direct sunlight; wear protective clothing, including a hat. Also, wear sunglasses.

• Caution needed for patients with GI symptoms, liver and kidney damage and during pregnancy.

What are the side effects of Clofazimine?

Skin- Pigmentation from pink to brownish-black, scaly skin and dryness, rash and itching.
Gastrointestinal- Abdominal pain, diarrhea, nausea, vomiting, gastrointestinal intolerance.
Eye- Discoloration of cornea and conjunctiva along with dryness and irritation of the eyes.
Other- Discoloration of urine, feces, sputum, sweat, elevated blood sugar, elevated ESR(erythrocyte sedimentation rate).
Central Nervous System- Dizziness, drowsiness, fatigue, headache, giddiness, nerve pain, taste disorder.

What are the other precautions for Clofazimine?

Do not change the dosage without your doctor's advice.

What are the storage conditions for Clofazimine?

Oral: Store below 30°C. Store it in airtight container and keep away from children.

Schedule : H
Prescription drugs - Drugs to be sold only under the prescription of a Registered Medical Practitioner.
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