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Generic Name : Clofazimine
Pronunciation : kloe-FAZ-i-meen
Therapeutic Classification : antileprotics
Trade Name(s):
India- Clofozine Cap, Clofamin, Fazim, Feza, Clofaz, Hansepran Cap. International- Lamprene. This medication is an anti-inflammatory agent, prescribed for leprosy with other drugs. It is also used to treat reactions to anti – leprosy drugs. When it is not to be taken (Contraindications):
When it is to be taken : Multibacillary Leprosy treatment: 50 mg daily plus 300 mg once a month along with other antileprosy drugs for 1 year. Reactions in Leprosy: Treatment depends on severity. 100-200 mg/day for up to 3 month. How it should be taken : It comes as a capsule to take by mouth once a day, with or without food. Special Instruction : *It may cause dizziness, drowsiness. Do not drive a car or operate machinery while taking this medication. *It may cause a red to brownish black discoloration of skin, mucous membranes and secretions. *Avoid direct sunlight; wear protective clothing, including a hat. Also, wear sunglasses. *Caution needed for patients with GI symptoms, liver and kidney damage and during pregnancy. Side Effects : Skin- Pigmentation from pink to brownish-black, scaly skin and dryness, rash and itching. Gastrointestinal- Abdominal pain, diarrhea, nausea, vomiting, gastrointestinal intolerance. Eye- Discoloration of cornea and conjunctiva along with dryness and irritation of the eyes. Other- Discoloration of urine, feces, sputum, sweat, elevated blood sugar, elevated ESR(erythrocyte sedimentation rate). Central Nervous System- Dizziness, drowsiness, fatigue, headache, giddiness, nerve pain, taste disorder. *Do not change the dosage without your doctor's advice. Storage Conditions : Oral: Store below 30°C. Store it in airtight container and keep away from children. |
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