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Clindamycin and Tretinoin

Latest prescription information about Clindamycin and Tretinoin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Clindamycin and Tretinoin
Pronunciation : klin da MYE sin TRET i noyn
Therapeutic Classification : Anti- Infectives
ICD Code : Y41.8
Trade Name(s): 
International- Ziana, Veltin.
Why it is prescribed (Indications) : 
This combination medication contains antibiotic and retinoid, prescribed for acne. Tretinoin reduces the amount of oil released by oil glands.
When it is not to be taken (Contraindications): Contraindicated in patients with stomach or bowel inflammation, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Topical- Apply over the face at bedtime.
How it should be taken : 
It comes as gel to apply topically, as directed by your physician.
Warnings and Precautions : 
* Caution should be exercised in patients with history of open wound, sunburn, or damaged skin, eczema, high white blood cell counts, stomach or bowel problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* Avoid exposure to sunlight.
* For external use only; avoid contact with eyes.
Side Effects : 
Redness of the skin, scaling, itching, burning, and stinging.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store at 25°C. Protect from light. Protect from freezing.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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