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Clemastine

Latest prescription information about Clemastine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Clemastine
Pronunciation : klem' as teen
Therapeutic Classification : Antihistamines
ICD Code : Y43.0
Trade Name(s): 
India- Clamist Syr , Clamist Tab, Taregyl Syr, Taregyl Tab, Tavegyl Syr , Tavegyl Tab.
International- Allerhist-1 and Tavist-1.
Why it is prescribed (Indications) : This medication is an antihistamine and anticholinergic agent, prescribed for allergic rhinitis. It is also used for uricaria and angioedema. This medication inhibits the effect of histamines in the body.  
When it is not to be taken (Contraindications): Contraindicated in patients with increased eye pressure, breastfeeding women, newborns and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : Adult: PO- Allergic conditions- 1 mg twice daily, up to 6 g/day.
IV- Prophylaxis of acute allergic conditions- 2 mg/day.
IV/IM- Acute allergic reactions- 4 mg/day.
How it should be taken : It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of asthma or other respiratory problems, increased eye pressure, ulcer, difficulty in urinating, blockage of the stomach, intestine, or urinary tract, heart disease, high blood pressure, seizures, overactive thyroid, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
Side Effects : 
Central Nervous System - Drowsiness, CNS depression, dizziness and sedation.
Gastrointestinal - Diarrhea, constipation, nausea and vomiting.
Heart - Low blood pressure, headache, palpitations and fast heart rate.
Genitourinary - Urinary frequency, difficult urination, urinary retention and early menses.
Miscellaneous - Blurred vision, thickened respiratory secretions and ringing in the ear.
Other Precautions : 
* Avoid maximum sun exposure.
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature, away from direct sunlight. Keep away from children.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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