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Generic Name : Cisplatin
Pronunciation : sis' pla tin
Therapeutic Classification : Chemotherapy
Trade Name(s):
India- Blastolem Vial, Cadiplat Vial, Celpat Inj, Cisget Vial, Cisplan Vial, Cisplat Infusion, Cisplatin Vial, Cisteen Vial, Cistriz Vial, Cytoplatin Inj, Duplat Inj, Kemoplat Inj, Neoplat Vial, Oncoplatin-Aq Inj, Platicis Inj, Platikem Vial, Platin 10mg Inj, Platinex Vial, Plationco Vial, Tevaplatin Inj, Tumotin Inj, Uniplatin Vial. International- Platinol. When it is not to be taken (Contraindications): Contraindicated in patients with hearing impairment, kidney impairment and hypersensitivity.
When it is to be taken : Adult: IV- Metastatic ovarian cancer As monotherapy: 100 mg/m2 per cycle, given as a single dose once every 4 week. For combination therapy with cyclophosphamide: 75-100 mg/m2 on day 1 of every 4-week cycle. Metastatic testicular tumors 20 mg/m2/day for 5 days per cycle. Advanced bladder cancer 50-70 mg/m2 per cycle once every 3-4 week. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Special Instruction : * Caution should be exercised in patients with history of bone marrow suppression, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast-feeding. * Monitor complete blood counts, ear and neurological functions regularly while taking this medication. * Patients may develop with increased risk of nephrotoxicity (kidney damage with irritation), drink adequate fluids to prevent damage. * Avoid vaccination while taking this medication. * It may develop new type of cancer; if you have any doubt consult with your doctor regarding this. Side Effects : Toxic effects - Nephrotoxicity (kidney damage) and ototoxicity (ear damage). Severe effects - Stroke, heart attack, electrolyte disturbances and allergic reactions. Gastrointestinal - Loss of appetite, nausea and vomiting. ENT - Ringing in the ear, loss of hearing and deafness. * Avoid excess dosage. Storage Conditions : This drug is used only under the supervision of physician. |
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