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Cisplatin

Latest prescription information about Cisplatin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Cisplatin
Pronunciation : sis' pla tin
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Blastolem Vial, Cadiplat Vial, Celpat Inj, Cisget Vial, Cisplan Vial, Cisplat Infusion, Cisplatin Vial, Cisteen Vial, Cistriz Vial, Cytoplatin Inj, Duplat Inj, Kemoplat Inj, Neoplat Vial, Oncoplatin-Aq Inj, Platicis Inj, Platikem Vial, Platin 10mg Inj, Platinex Vial, Plationco Vial, Tevaplatin Inj, Tumotin Inj, Uniplatin Vial.
International- Platinol.
Why it is prescribed (Indications) : This medication is a platinum-based chemotherapy agent, prescribed for ovarian cancer, bladder cancer and metastatic testicular tumors either alone or with other medications.

When it is not to be taken (Contraindications): 

Contraindicated in patients with hearing impairment, kidney impairment and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : Adult: IV- Metastatic ovarian cancer As monotherapy: 100 mg/m2 per cycle, given as a single dose once every 4 week.
For combination therapy with cyclophosphamide: 75-100 mg/m2 on day 1 of every 4-week cycle. Metastatic testicular tumors 20 mg/m2/day for 5 days per cycle. Advanced bladder cancer 50-70 mg/m2 per cycle once every 3-4 week.
How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction : 
* Caution should be exercised in patients with history of bone marrow suppression, kidney or liver disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast-feeding.
* Monitor complete blood counts, ear and neurological functions regularly while taking this medication.
* Patients may develop with increased risk of nephrotoxicity (kidney damage with irritation), drink adequate fluids to prevent damage.
* Avoid vaccination while taking this medication.
* It may develop new type of cancer; if you have any doubt consult with your doctor regarding this.
Side Effects : 
Toxic effects - Nephrotoxicity (kidney damage) and ototoxicity (ear damage).
Severe effects - Stroke, heart attack, electrolyte disturbances and allergic reactions.
Gastrointestinal - Loss of appetite, nausea and vomiting.
ENT - Ringing in the ear, loss of hearing and deafness.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
This drug is used only under the supervision of physician.

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