Cholestyramine Resin - Drug Information

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General Information on Cholestyramine Resin

Generic Name : Cholestyramine Resin

Pronunciation : koe less' tir a meen

Latest prescription information about Cholestyramine Resin. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y52.6 | Therapeutic Classification : Antilipemics

Trade Names/Brand Names of Cholestyramine Resin

International-Prevalite, Locholest Questran.

Why is Cholestyramine Resin Prescribed? (Indications)

This medication is a bile acid sequestrant, prescribed for high cholesterol. This medication reduces cholesterol level in the blood.  

When should Cholestyramine Resin not to be taken? (Contraindications)

Contraindicated in patients with intestinal obstruction and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Cholestyramine Resin?

Adults - PO- Initial: 1 scoop or single-use packet (4 g anhydrous cholestyramine) daily to twice daily. Maintenance: 2 to 4 packets or scoops daily, divided into 2 doses.
Children - PO- usual dose is 240 mg/kg/day.

How should Cholestyramine Resin be taken?

It comes as a powder with dosage measurement cup or in individual dose packets to take by mouth with food.

What are the warnings and precautions for Cholestyramine Resin?

Caution should be exercised in patients with history of heart disease, chest pain, stomach, intestinal or gallbladder disease, phenylketonuria (genetic disorder), any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Monitor lipid and cholesterol levels and prothrombin time regularly while taking this medication.

What are the side effects of Cholestyramine Resin?

   Skin : Skin irritation and rash.
   Gastrointestinal : Constipation, bloating, stomach pain, gas, stomach upset, vomiting, diarrhea, loss of appetite, heartburn and indigestion.
   Blood : Bleeding tendencies related to vitamin K deficiency and folic acid deficiency.
   Metabolic-Nutritional : Fat-soluble vitamin deficiencies, acidity and osteoporosis.

What are the other precautions for Cholestyramine Resin?

Avoid excess dosage.

What are the storage conditions of Cholestyramine Resin?

Store it at controlled room temperature (20-25C).

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