Chlorpropamide - Drug Information

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General Information on Chlorpropamide

Generic Name : Chlorpropamide

Pronunciation : klor proe' pa mide

Latest prescription information about Chlorpropamide. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.3 | Therapeutic Classification : Antidiabetics

Trade Names/Brand Names of Chlorpropamide

India : 

International : 

Chlorformin, Diabinese, Glucamide

Why is Chlorpropamide Prescribed? (Indications)

This medication is a sulfonylurea antidiabetic drug, prescribed for type 2 diabetes. This medication helps to keep blood sugar levels under control.  

When should Chlorpropamide not to be taken? (Contraindications)

Contraindicated in patients with type 1 diabetes and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Chlorpropamide?

PO- The recommended initial dose is 250mg/day. It may be adjusted based on patient’s condition.

How should Chlorpropamide be taken?

It comes as a tablet to take by mouth, with food.

What are the warnings and precautions for Chlorpropamide?

• Caution should be exercised in patients with history of heart, liver, kidney, thyroid, adrenal or pituitary disease, any allergy, who are taking other medications, elderly, children, during pregnancy and breast feeding.
• It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
• Avoid drinking alcoholic beverages and smoking while taking this medication.
• Avoid exposure to sunlight; otherwise it may lead to sunburn.
• It may cause low blood sugar with the following symptoms: weakness, fainting, anxiety, dizziness or drowsiness, if it is so consult with your physician.
• Follow proper diet and exercise program as directed by your physician.

What are the side effects of Chlorpropamide?

•   Body as a Whole : Low blood sugar, Disulfiram-like
•   Central Nervous System : Dizziness and headache.
•   Gastrointestinal : Diarrhea, nausea, vomiting, loss of appetite and hunger.
•   Liver : Jaundice.
•   Skin : Itching and hives.
•   Blood : Anemia and decrease in blood counts.

What are the other precautions for Chlorpropamide?

Avoid excess dosage.

What are the storage conditions of Chlorpropamide?

Store it at room temperature, and in an airtight container. Keep away from children.


Schedule : G

Drugs that are to be used only under medical supervision.

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