Chloral Hydrate - Drug Information

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General Information on Chloral Hydrate

Generic Name : Chloral Hydrate

Pronunciation : klor al hi' drate

Latest prescription information about Chloral Hydrate. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y47.5 | Therapeutic Classification : Anxiolytics, Sedatives And Hypnotics

Trade Names/Brand Names of Chloral Hydrate

International- Aquachloral, Noctec.

Why is Chloral Hydrate Prescribed? (Indications)

This medication is an effective sedative and hypnotic agent, prescribed for insomnia. It works by depressing the central nervous system.

When should Chloral Hydrate not to be taken? (Contraindications)

Contraindicated in patients with marked liver or kidney impairment, heart disease and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Chloral Hydrate?

Adult- Hypnotic- The recommended dose is 500 mg to 1 g, taken 15 to 30 minutes before bedtime or surgery.
Sedative The recommended dose is 250 mg 3 times/day after meals.
Child- Hypnotic- The recommended dose is 50 mg/ kg/day as a single dose.
Sedative- 25mg/kg/day.

How should Chloral Hydrate be taken?

It comes as a capsule, oral liquid to take by mouth with food.

What are the warnings and precautions for Chloral Hydrate?

Caution should be exercised in patients with history of throat inflammation, ulcer, blood disorder, depression, suicidal thoughts, alcohol abuse, any allergy, who are taking other medications, children, during pregnancy and breast-feeding.
It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.

What are the side effects of Chloral Hydrate?

   Central Nervous System : Excitement, tolerance, addiction, mental illness, drowsiness, staggering gait, incoordination, lightheadedness, fainting, dizziness, nightmares, uneasiness, mental confusion and hallucinations.
   Blood : Decrease in white blood cells and increased eosinophilia.
   Skin : Allergic skin rashes including hives, redness and inflammation.
   Gastrointestinal : Gastric irritation, nausea, vomiting, flatulence, diarrhea, and unpleasant taste.
   Miscellaneous : Rarely headache, hangover and idiosyncratic syndrome can occur.

What are the other precautions for Chloral Hydrate?

Avoid excess dosage.

What are the storage conditions of Chloral Hydrate?

Store it at controlled room temperature (15-30 C) and in an airtight container, keep away from children.

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