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Generic Name : Cetuximab
Pronunciation : seh TUX ih mab
Trade Name(s):
International- Erbitux. When it is not to be taken (Contraindications): Hypersensitivity.
When it is to be taken : Monotherapay- The recommended initial dose is 400 mg/m2 administered as a 120-minute intravenous infusion (maximum infusion rate 10 mg/min). With radiation therapy- Adult- IV- The recommended initial dose is 400 mg/m2 administered one week prior to initiation of a course of radiation therapy as a 120-minute intravenous infusion (maximum infusion rate 10 mg/min). Maintenance: 250mg/m2. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein. Special Instruction : * Caution should be exercised in patients with history of abnormal blood electrolyte levels, lung or breathing problems, respiratory tract infection, heart failure, or irregular heartbeat, any allergy, who are taking other medications, children, during pregnancy and breast-feeding. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. * Avoid exposure to sunlight. Side Effects : Most Common - Rash, itching, nail changes, headache, diarrhea and infections. Serious Effects - Heart arrest, kidney failure, blood clot in lungs and skin damage. Body as a Whole - Weakness, fever, headache, infection and chills. Gastrointestinal - Nausea, nosebleed, diarrhea and indigestion. Metabolic - Weight loss, dehydration, increase in liver enzyme levels. Respiratory - Inflammation of pharynx. * Avoid excess dosage. Storage Conditions : Store it in refrigerator (2°C to 8°C). Do not freeze it. |
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