Information about Certolizumab
Generic Name : CertolizumabUp-to-date prescription details regarding Certolizumab are provided here.
Pronunciation : SER-toe-LIZ-ue-mab
Learn the correct pronunciation of the Certolizumab, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.
ICD Code : Y43.4 Therapeutic Classification : Monoclonal antibodies
Trade Names/Brand Names of Certolizumab
International :
Cimzia
Why is Certolizumab Prescribed? (Indications)
This medication is a therapeutic monoclonal antibody, prescribed for Crohn's disease and rheumatoid arthritis. It blocks the activity of a protein named as TNF-alpha in the body.When should Certolizumab not be taken? (Contraindications)
Hypersensitivity.What is the dosage of Certolizumab?
Crohn's Disease- The recommended initial adult dose is 400 mg (given as two subcutaneous injections of 200 mg) initially, and at weeks 2 and 4.Rheumatoid Arthritis- The recommended dose is 400 mg (given as two subcutaneous injections of 200 mg) initially and at weeks 2 and 4.
How should Certolizumab be taken?
It comes as a solution for injection, to be administered by a healthcare provider under the skin.What are the warnings and precautions for Certolizumab?
•♦ Caution should be exercised in patients with history of hepatitis B, other liver problems, diabetes, heart problems, nervous system problems, poor immunity, bone marrow depression, cancer, tuberculosis, Hepatitis B, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.• Avoid contact with people who have infections that can be spread to others.
• It may reduce platelet counts; avoid bruising or injury.
• Monitor TB tests, complete blood cell counts and liver function regularly while taking this medication.
• Avoid live vaccination during the treatment period.
♦ Patient may develop with increased risk of cancer and serious infections; consult with your healthcare provider before taking this medication.
What are the side effects of Certolizumab?
Most Common - Abdominal pain, diarrhea, and intestinal obstruction.Blood - Anemia, decrease in white blood cells and platelets.
Heart - Chest pain, abnormal heart rhythm, high blood pressure, heart failure, heart attack, stroke and transient ischemic attack and inflammation of blood vessels.
Eye - Eye bleeding and inflammation.
General - Bleeding and injection site reactions.
Liver - Elevated liver enzymes and liver inflammation.
Central Nervous System - Anxiety, bipolar disorder, and suicide attempt.
Genitourinary - Nephrotic syndrome and kidney failure and menstrual disorder.
Skin - Skin inflammation, redness, and hives.
♦Immune System Disorders - Sarcoidosis
