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Carvedilol

Latest prescription information about Carvedilol. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Carvedilol
Pronunciation : kar-VE-dil-ol
Therapeutic Classification : Beta- Adrenergic Blockers
ICD Code : Y51.7
Trade Name(s): 
India- Caditone Tab, Cadmos Tab, Carca Tab, Cardivas Tab, Carelol Tab, Carloc Tab, Cartab Tab, Carvas Tab, Carvedil Tab, Carvel Tab, Carvetrend Tab, Carvil Tab, Carvimed Tab, Carvipress Tab , Carvizest Tab, Carzec Tab, Caslot Tab, Cevas Tab, Conpres Tab, Cvl Tab, Oricar Tab, Ved Tab, Coslot.
international- Coreg, Coreg CR.
Why it is prescribed (Indications) : 
This medication is an alpha- and beta-blocker, prescribed for heart failure and high blood pressure.  It relaxes blood vessels and slowing heart rate to improve blood flow and decreases blood pressure.
When it is not to be taken (Contraindications): 
Hypersensitivity; severe chronic heart failure, bronchial asthma or similar conditions, severe liver damage.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Oral- Hypertension- Adult: Initially, 12.5 mg once daily increased to 25 mg once daily after 2 days. Alternatively, initial dose of 6.25 mg bid increased to 12.5 mg bid after 1-2 wk, increased further if necessary to 50 mg once daily or in divided doses. Elderly: 12.5 mg once daily.
Angina pectoris- Adult: Initially, 12.5 mg bid increased to 25 mg bid after 2 days.
Heart failure- Adult: Initially, 3.125 mg bid, doubled to 6.25 mg bid after 2 wk if tolerated, then gradually increased to the max dose the patient can tolerate at intervals of not <2 wk. Max dose: >85 kg: 50 mg bid; <85 kg: 25 mg bid.
Left ventricular dysfunction post myocardial infarction- Adult: Initially: 6.25 mg bid, if tolerated, after 3-10 days, increase to 12.5 mg bid and then to a target dose of 25 mg bid.
How it should be taken : 
It comes as a tablet and an extended-release (long-acting) capsule to take by mouth. The tablet is usually taken twice a day with food.
Warnings and Precautions : 
*Avoid abrupt withdrawal sometimes heart attack may occur if you suddenly stop it.
*It may cause dizziness, lightheadedness, or fainting. Do not drive a car or operate machinery while taking this medication.
*Caution needed during pregnancy and lactation.
Side Effects : 
Gastrointestinal- Diarrhea, nausea, vomiting.
Central Nervous System- Dizziness, fatigue, headache, lightheadedness, disorientation, fainting.
Heart- Chest pain, irregular or unusually slow heartbeat.
Eye- Dry eyes, persistent or severe vision changes.
Miscellaneous- Change in the amount of urine produced, fever, sudden, unusual weight gain; swelling of the hands, ankles, or feet; unusual bruising or bleeding.
Other Precautions : 
*Monitor blood pressure regularly.
Storage Conditions : 
Store below 30°C.keep away from children.

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Member Comments ( 3 )
i am a male aged 73 years.i had CABG IN 1998.Among several medicines prescribed at the time of my discharge,cardivas was one and i am advised to continue this medicine even now more than ten years after my surgery.My query is whether continuance of this medicine is necessary.my heart beat and pulse rate are normal.
(Posted by rvps40, India Date : 3/16/2013 )
The dryness of eyes is observed with blurred vision while taking this mediine
Abhay Keny Madgaon Goa

(Posted by abhaykeny, India Date : 2/12/2012 )
Blood pressure level drops as low as 90/60, but NO other complaints.
(Posted by sachys, Malaysia Date : 12/21/2010 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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