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Generic Name : Carmustine
Pronunciation : kar mus' teen
Therapeutic Classification : Chemotherapy
Trade Name(s):
International- BiCNU. When it is not to be taken (Contraindications): Hypersensitivity.
When it is to be taken : IV- The recommended dose as a single agent in previously untreated patients is 150 to 200 mg/m² intravenously every 6 weeks. This may be given as a single dose or divided into daily injections such as 75 to 100 mg/m² on 2 successive days. How it should be taken : It comes as a solution for injection, administered by healthcare providers. Special Instruction : * Avoid immunization while taking this medication. * If you are taking any other medication, inform the doctor. * Caution should be exercised in patients with history of liver or kidney impairment, decrease in blood count, bone marrow depression, lung disease, during pregnancy and breast-feeding. * Monitor blood count, liver, kidney and lung function regularly while taking this medication. * It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication. Side Effects : Body as whole- Fever, chills, sore throat, loss of appetite or weight and swelling in ankle and feet region. Skin - Pale skin, easy bruising and redness. Blood- Abnormal bleeding. Heart - Rapid heart beat. Respiratory - Wheezing and chest pain. Gastrointestinal- Nausea, vomiting and diarrhea. Central Nervous System- Confusion, headache, weakness, dizziness, drowsiness and mood changes. Eye - Vision imbalance. Delayed effect- Liver and kidney damage, lung fibrosis and stomach upset. Potentially Fatal- Delayed and cumulative bone marrow depression. * Avoid alcohol consumption while taking this medication. Storage Conditions : Store in refrigerator at 2-8°C; away from light. |
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