Generic Name : Carglumic Acid Pronunciation : kar-GLOO-mik AS-id Therapeutic Classification : Orphan Drug
International- Carbaglu. Why it is prescribed (Indications) :
This medication is similar to n-acetylglutamate (NAG), prescribed for hyperammonemia due to the deficiency of the liver enzyme named as N-acetylglutamate synthase (NAGS). It acts as a replacement for NAG. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
Adult- PO- The recommended initial dose is 100 mg/kg/day to 250 mg/kg/day. How it should be taken :
It comes as a tablet to take by mouth, immediately before meals. Warnings and Precautions :
* Caution needed for patients with any allergy, during pregnancy and breastfeeding.
* Follow the diet program as directed by your healthcare provider. Side Effects :
Most Common - Vomiting, abdominal pain, fever, tonsilitis, anemia, ear infection, diarrhea, throat inflammation, and headache.
Blood - Anemia.
ENT - Ear infection.
Gastrointestinal - Abdominal pain, diarrhea, vomiting, difficulty in swallowing.
General - Weakness, fever.
Infections - Infection, throat inflammation, pneumonia.
Metabolic - Loss of appetite, hemoglobin decreased, weight decreased.
Central Nervous System - Headache, drowsiness.
Skin - Rash.
* Avoid excess dosage. Storage Conditions :
Store it in refrigerator 2 - 8°C.
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