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Carbimazole

Latest prescription information about Carbimazole. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Carbimazole
Pronunciation : car-bim-a-zole
Therapeutic Classification : Thyroid and Antithyroid Agents
ICD Code : Y42.2
Trade Name(s): 
India- Antithyrox, Neomercarole, Thyrocab, Thyrozole.
International- Camazol, Car, Carbimazol Henning, Carbimazol Hexal, Carbimazol PCH, Carbimazol Ratiopharm, Carbimazol Slovakofarma, Carbimazol, Carbimazole Christo, Carbimazole Synco, Carbimazole, Carbistad, Cazole, Neo Tomizol, Neo-Mecrazole, Newmazole, Thyrostat, Tyrazol.
Why it is prescribed (Indications) : This medication is a pro-drug, prescribed for hyperthyroidism.  It reduces the amount of thyroid hormone.
When it is not to be taken (Contraindications): Contraindicated in patients with goiter and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : Initial dose: 15-45mg daily in divided doses for 2-4 weeks.
How it should be taken : It comes as a tablet and capsule to take by mouth with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver disease and during pregnancy and breast-feeding.
Side Effects : 
Sore throat, mouth ulcers, fever, bruising, uneasiness, jaundice, nausea, loss of taste, headache, joint pain and hair loss.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25oC).

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Member Comments ( 2 )
I have been diagnosed Hyperthyroidism and jaundice at the same time 2 weeks ago. My T3 was raised to nearly 5 with elisa method and total billirubin was 4.1.
and in this case my doctor prescribed me to take Neo-Mercazole 5 for ten days.After taking for 6 days I just searched for this drug on the net and found that in the case of higher billirubin this drug should be discontinued. So now what should I do. Please give me the expert advice.
Thanks.
Abdulkarim.salahuddin@gmail.com

(Posted by Abdulkarim, India Date : 8/19/2011 )
Carbimazole is found to be safe in lactating women and endorsed by AAP. Statement given above that it is contraindicated requires review.
(Posted by eric dsouza, India Date : 8/12/2008 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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