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Capecitabine

Latest prescription information about Capecitabine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Capecitabine
Pronunciation : Cap-eh-SIT-uh-bean
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Capecite Tab, Capiibine Tab, Captabin Tab, Capxcel Tab, Caxeta Tab , Citabin Tab, Naprocap Filcotab, Xabine Tab, Xelocel Film-Coated Tab, Xeloda Tab, Zocitab Tab.
International- Xeloda.
Why it is prescribed (Indications) : 
This medication is an antimetabolite, prescribed for breast cancer and colorectal cancer. It prevents the growth of cancer cells.

When it is not to be taken (Contraindications): 


Contraindicated in patients with kidney problems or dihydropyrimidine dehydrogenase (DPD) enzyme deficiency and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
The recommended dose is 1250 mg/m2 administered orally twice daily (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by 1-week rest period given as 3-week cycles.
How it should be taken : 
It comes as a tablet to take by mouth, with food, two times per day.
Special Instruction : 
* Caution should be exercised in patients with history of heart, liver or kidney disease, any allergy, bone marrow problems, pain, redness, swelling, tingling, tenderness of the palms and soles, who are taking other medications, elderly, children, during pregnancy and lactation.
* Avoid vaccination while taking this medication.
* It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
* It may reduce platelet counts; avoid bruising or injury.
* Monitor blood counts and blood electrolytes while taking this medication.
Side Effects : 
Gastrointestinal Disorders - Diarrhea, nausea, mouth ulcer, vomiting, abdominal pain, gastrointestinal hemorrhage constipation, upper abdominal pain and indigestion.
Skin - Hand-and-Foot Syndrome, hair loss, rash and redness.
General - Injection site pain, irritation, swelling, fatigue, fever, chest pain, back pain, weakness and lethargy.
Central Nervous System - Dizziness, depression, sleep disorders, headache and abnormal taste.
Metabolic - Loss of appetite.
Eye - Eye inflammation and loss of vision.
Blood - Decreased white blood cells.
Respiratory - Nosebleed, cough and sore throat.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature 25oC.

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