Calcitriol - Drug InformationGeneric Name : Calcitriol | Pronunciation : KAL-si-TRYE-ol
Why it is prescribed (Indications) :
This medication is a synthetic vitamin D analog, prescribed for hypocalcemia in patients undergoing chronic renal dialysis. It helps proper absorption and use of calcium and phosphate in the body.
When it is not to be taken (Contraindications):
Contraindicated in patients with vitamin D toxicity and hypersensitivity.
Pregnancy Category :
Category C :Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Dosage & When it is to be taken :
PO- The recommended initial dose is 1 mcg (0.02 mcg/kg) to 2 mcg administered three times weekly, approximately every other day.
How it should be taken :
It comes as a tablet and capsule to take by mouth, with or without food.
Warnings and Precautions :Caution should be exercised in patients with history of heart, kidney disease, kidney stones, hardening of the arteries, high phosphate level in the blood, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
It may cause drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid excess dosage.
It may lead to dehydration, drink enough fluid.
Side Effects :
Central Nervous System - Weakness, headache, sensory disturbances, muscle weakness, mood changes and drowsiness.
Gastrointestinal - Nausea, vomiting, dry mouth, constipation, metallic taste, loss of appetite, abdominal pain or stomach pain.
Musculoskeletal - Muscle pain and bone pain.
Genitourinary - Nighttime urination, frequent urination, urinary tract infection and Blood urea nitrogen.
Metabolic - Weight loss, increased thirst, dehydration, increased fat in blood and elevated liver enzymes.
Eye and ENT - Eye inflammation and photophobia.
Heart - High blood pressure and abnormal heart rhythm.
Central Nervous System - Muscle weakness and mood changes.