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Busulphan
Latest prescription information about Busulphan. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Busulphan
Pronunciation : byoo sul' fan
Therapeutic Classification : Chemotherapy
Trade Name(s):
India- Bucelon Amp, Bucelon Film-Coated Tab, Busulfan Tab , Busuphan Tab, Mylefan Tab, Myleran Tab , Myran Tab , Mysulfan Tab. International- Busulfex. This medication is a chemotherapy agent, prescribed for chronic myelogenous leukemia. It is also used for bone marrow transplantation. When it is not to be taken (Contraindications):
When it is to be taken : Adult: PO- Palliation of chronic myeloid leukaemia- 60 mcg/kg/day. Maintenance: 0.5-2 mg/day. Max: 4 mg/day. How it should be taken : It comes as a tablet to take by mouth, with or without food. Special Instruction : * Caution should be exercised in patients with history of bone marrow depression, blood problems, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. * Avoid alcohol consumption. * Avoid vaccination. * Monitor blood counts, sugar level regularly during therapy. * It may cause lung toxicity; if so stop the medication. * It may cause infertility, consult with your doctor for any queries. Side Effects : Body As A Whole - Fever, headache, weakness, chills, pain, swelling, general allergic reactions, chest pain, inflammation at injection site and back pain. Heart - Fast heart rate and dilatation of blood cells. Gastrointestinal - Nausea, mouth ulcer, vomiting, loss of appetite, diarrhea, abdominal pain, indigestion, constipation, dry mouth, rectal disorder and abdominal enlargement. Metabolic - Decrease in magnesium/glucose/potassium/calcium and increase in liver enzyme levels. Central Nervous System - Sleeplessness, anxiety, dizziness and depression. Respiratory - Nose inflammation, lung disorder, cough, nosebleed and difficulty in breathing. Skin - Rash and itching. * It may cause ovarian failure and may stop girls from reaching puberty. Storage Conditions : Store it at room temperature and away from excess heat and moisture. Keep away from children. |
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